ArticleBMC endocrine disorders2022
Association between triglyceride-glucose index and nonalcoholic fatty liver disease in type 2 diabetes mellitus.
Article in BMC endocrine disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Association between atherogenic index of plasma and MASLD in patients with type 2 diabetes: a cross-sectional study.BMC endocrine disorders · 2026Article
- Triglyceride-glucose and TyG-BMI indexes predict acute pancreatitis in adult critically ill patients admitted to intensive care.Clinics (Sao Paulo, Brazil) · 2026Article
- Review
- Interpreting the triglyceride-glucose index and its derived indices in metabolic dysfunction-associated steatotic liver disease: clinical utility and evidence gaps.Frontiers in medicine · 2026Review
- The Importance of Serum Perilipin-2 Level as an Early Indicator of Inflammation in Non-Alcoholic Fatty Liver Disease.Diagnostics (Basel, Switzerland) · 2025Article
- Association between triglyceride-glucose index and liver enzymes in adults with metabolic syndrome: a retrospective cross-sectional study.Annals of medicine · 2025Article
- Evaluation of the Relationship Between Albuminuria and Triglyceride Glucose Index in Patients with Type 2 Diabetes Mellitus: A Retrospective Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2025Article
- The effect of longitudinal trajectories of triglyceride-glucose index on the incident metabolic dysfunction-associated steatotic liver disease.BMC gastroenterology · 2025Article
- The Ability of the Triglyceride-Glucose (TyG) Index and Modified TyG Indexes to Predict the Presence of Metabolic-Associated Fatty Liver Disease and Metabolic Syndrome in a Pediatric Population with Obesity.Journal of clinical medicine · 2025Article
- Triglyceride-glucose index as a marker in cardiovascular diseases; a bibliometric study and visual analysis.Annals of medicine and surgery (2012) · 2025Review
- Association between the triglyceride-glucose index and liver fibrosis in adults with metabolism-related fatty liver disease in the United States: a cross-sectional study of NHANES 2017-2020.BMC gastroenterology · 2025Article
- Non-Alcoholic Fatty Liver Disease or Type 2 Diabetes Mellitus-The Chicken or the Egg Dilemma.Biomedicines · 2023Review
- The triglyceride glucose-waist-to-height ratio outperforms obesity and other triglyceride-related parameters in detecting prediabetes in normal-weight Qatari adults: A cross-sectional study.Frontiers in public health · 2023Article
- Modified triglyceride-glucose index indices are reliable markers for predicting risk of metabolic dysfunction-associated fatty liver disease: a cross-sectional study.Frontiers in endocrinology · 2023Article
- A non-linear relationship between triglyceride glucose waist circumference and nonalcoholic fatty liver disease in a Japanese population: a secondary analysis.Frontiers in endocrinology · 2023Article
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9 authors.
Funding
Abstract
backgroundLipid and glucose metabolism abnormalities are associated with nonalcoholic fatty liver disease (NAFLD). The triglyceride-glucose (TyG) index is a recently developed indicator that can identify individuals at risk for NAFLD. However, the applicability of the TyG index for identifying NAFLD in patients with type 2 diabetes mellitus (T2DM) is unclear. The aim of this study was to investigate the ability of the TyG index to identify individuals at risk for NAFLD in the T2DM population.
methodsA total of 2280 participants with T2DM were recruited in this cross-sectional study. The TyG index was calculated, and NAFLD was diagnosed by ultrasonography. Binary logistic regression models were used to evaluate the association of the TyG index, glycemic parameters and lipid parameters with NAFLD.
resultsLogistic regression analysis showed that the TyG index was significantly associated with NAFLD in subjects with T2DM, the odds ratio (OR) were 3.27 (95% confidence interval [CI], 2.03-5.27; P < 0.001) for NAFLD in the highest TyG quartile after adjustment for known confounders. In stratified analysis, an elevated TyG index were more remarkably associated with NAFLD in younger patients (< 65 years; OR, 2.35; 95% CI, 1.83-3.02; P < 0.001), females (OR, 2.69; 95% CI, 1.67-4.32; P < 0.001), patients with BMI < 25 kg/m
conclusionThe TyG index is significantly associated with NAFLD and shows superior ability for identify NAFLD risk compared with other lipid and glycemic parameters in T2DM.
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