Evidence map›Paper›PMID 36289306›Full record

ArticleScientific reports2022

Greater central airway luminal area in people with COVID-19: a case-control series.

Jeffrey L Jeltema, Ellen K Gorman, Erik A Ovrom, Juan G Ripoll, Paolo B Dominelli, Michael J Joyner, Brian T Welch, Jonathon W Senefeld, Chad C Wiggins

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jeffrey L Jeltema *Alix School of Medicine, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0001-8445-0671
Ellen K Gorman *Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.ORCID 0000-0003-2989-547X
Erik A OvromAlix School of Medicine, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-5661-0698
Juan G RipollDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.ORCID 0000-0003-4908-9774
Paolo B DominelliDepartment of Kinesiology, University of Waterloo, Waterloo, ON, Canada.ORCID 0000-0001-5575-4043
Michael J JoynerDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.ORCID 0000-0002-7135-7643
Brian T WelchDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0003-2092-3163
Jonathon W SenefeldDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. senefeld.jonathon@mayo.edu.ORCID 0000-0001-8116-3538
Chad C WigginsDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. wiggins.chad@mayo.edu.ORCID 0000-0002-6458-0142
Mayo Clinic · USMayo Clinic in Arizona · USUniversity of Waterloo · CA

Funding

Variant Hemoglobin and Cardiorespiratory Regulation in HumansR35HL139854 · NHLBI · MAYO CLINIC ROCHESTER · PI JOYNER, MICHAEL J · 2018 to 2024
$5.8M
Skeletal muscle performance and cellular adaptations to high hemoglobin-oxygen affinityF32HL154320 · NHLBI · MAYO CLINIC ROCHESTER · PI SENEFELD, JONATHON · 2020 to 2021
$117k
NHLBI NIH HHS F32 HL154320NHLBI NIH HHS R35 HL139854
6 · The paper itself

Abstract

Respiratory epithelium in the conducting airways of the human body is one of the primary targets of SARS-CoV-2 infection, however, there is a paucity of studies describing the association between COVID-19 and physical characteristics of the conducting airways. To better understand the pathophysiology of COVID-19 on the size of larger conducting airways, we determined the luminal area of the central airways in patients with a history of COVID-19 compared to a height-matched cohort of controls using a case-control study design. Using three-dimensional reconstruction from low-dose high-resolution computed tomography, we retrospectively assessed airway luminal cross-sectional area in 114 patients with COVID-19 (66 females, 48 males) and 114 healthy, sex- and height-matched controls (66 females, 48 males). People with a history of smoking, cardiopulmonary disease, or a body mass index greater than 40 kg·m

Indexed as

COVID-19Case-Control StudiesFemaleHumansLungMaleRetrospective StudiesSARS-CoV-2

Identifiers

PMID36289306
PMCPMC9606286
OpenAlexW4307565851

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.