Evidence map›Paper›PMID 36289269›Full record

ArticleScientific reports2022

Impact of somatostatin interneurons on interactions between barrels in plasticity induced by whisker deprivation.

G Dobrzanski, R Zakrzewska, M Kossut, M Liguz-Lecznar

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

G DobrzanskiNencki Institute of Experimental Biology, Polish Academy of Sciences, Pasteur 3, 02-093, Warsaw, Poland. g.dobrzanski@nencki.edu.pl.
R ZakrzewskaNencki Institute of Experimental Biology, Polish Academy of Sciences, Pasteur 3, 02-093, Warsaw, Poland.
M KossutNencki Institute of Experimental Biology, Polish Academy of Sciences, Pasteur 3, 02-093, Warsaw, Poland.
M Liguz-LecznarNencki Institute of Experimental Biology, Polish Academy of Sciences, Pasteur 3, 02-093, Warsaw, Poland.
Polish Academy of Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The activity of inhibitory interneurons has a profound role in shaping cortical plasticity. Somatostatin-expressing interneurons (SOM-INs) are involved in several aspects of experience-dependent cortical rewiring. We addressed the question of the barrel cortex SOM-IN engagement in plasticity formation induced by sensory deprivation in adult mice (2-3 months old). We used a spared vibrissa paradigm, resulting in a massive sensory map reorganization. Using chemogenetic manipulation, the activity of barrel cortex SOM-INs was blocked or activated by continuous clozapine N-oxide (CNO) administration during one-week-long deprivation. To visualize the deprivation-induced plasticity, [

Indexed as

Somatosensory CortexVibrissaeAnimalsDeoxyglucoseInterneuronsMiceNeuronal PlasticitySomatostatinDeoxyglucoseSomatostatin

Identifiers

PMID36289269
PMCPMC9605983
OpenAlexW4307565772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.