Evidence map›Paper›PMID 36289148›Full record

ArticleWorld journal of microbiology & biotechnology2022

Cacti as low-cost substrates to produce L-asparaginase by endophytic fungi.

Leticia Francisca da Silva, Ana Patrícia Sousa Lopes de Pádua, Layanne de Oliveira Ferro, Gualberto Segundo Agamez-Montalvo, Jadson Diogo Pereira Bezerra, Keila Aparecida Moreira, Cristina Maria de Souza-Motta

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of microbiology & biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Leticia Francisca da SilvaDepartamento de Micologia Prof. Chaves Batista, Universidade Federal de Pernambuco (UFPE), Rua Prof. Nelson Chaves, s/n, Cidade Universitária, CEP: 50670-901, Recife, Pernambuco, Brazil.ORCID http://orcid.org/0000-0002-8939-8267
Ana Patrícia Sousa Lopes de PáduaDepartamento de Micologia Prof. Chaves Batista, Universidade Federal de Pernambuco (UFPE), Rua Prof. Nelson Chaves, s/n, Cidade Universitária, CEP: 50670-901, Recife, Pernambuco, Brazil.ORCID http://orcid.org/0000-0002-0058-8831
Layanne de Oliveira FerroDepartamento de Micologia Prof. Chaves Batista, Universidade Federal de Pernambuco (UFPE), Rua Prof. Nelson Chaves, s/n, Cidade Universitária, CEP: 50670-901, Recife, Pernambuco, Brazil.ORCID http://orcid.org/0000-0003-3757-0085
Gualberto Segundo Agamez-MontalvoDepartamento de Estatística e Matemática Aplicada, Universidade Federal do Ceará (UFC), Av. Mister Hull, s/n, Pici, CEP: 60455-760, Fortaleza, Ceará, Brazil.ORCID http://orcid.org/0000-0001-8561-8843
Jadson Diogo Pereira BezerraLaboratório de Micologia, Departamento de Biociências e Tecnologia, Instituto de Patologia Tropical e Saúde Pública (IPTSP), Universidade Federal de Goiás (UFG), Rua 235, s/n, Setor Universitário, CEP: 74605-050, Goiânia, Goiás, Brazil. jadsonbezerra@ufg.br.ORCID http://orcid.org/0000-0002-7782-8602
Keila Aparecida MoreiraLaboratório de Microbiologia, Tecnologia Enzimática e Bioprodutos, Universidade Federal do Agreste de Pernambuco (UFAPE), Av. Bom Pastor, s/n, Boa Vista, CEP: 55292-278, Garanhuns, Pernambuco, Brazil.ORCID http://orcid.org/0000-0002-7715-9285
Cristina Maria de Souza-MottaDepartamento de Micologia Prof. Chaves Batista, Universidade Federal de Pernambuco (UFPE), Rua Prof. Nelson Chaves, s/n, Cidade Universitária, CEP: 50670-901, Recife, Pernambuco, Brazil. cristina.motta@ufpe.br.ORCID http://orcid.org/0000-0002-0964-8271
Universidade Federal de Pernambuco · BRUniversidade Federal de Goiás · BRUniversidade Federal do Ceará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to select endophytic fungi to produce L-asparaginase and partially optimising the production of the enzyme using cacti as substrate. Seventeen endophytes were assessed for intracellular enzymatic potential in modified Czapek Dox's medium using L-proline as an inducer. The best producer was evaluated for intracellular and extracellular enzymatic activity in modified Czapek Dox's medium using flours of Opuntia ficus-indica and Nopalea cochenillifera as substrate. The biomass and L-asparaginase production profile was analysed and the best conditions for enzyme production were verified using factorial design. Penicillium decaturense URM 7966, Diaporthe ueckerae URM 8321, and Colletotrichum annellatum URM 8538 produced 0.76 U g

Indexed as

AsparaginaseCactaceaeFungiProlineAsparaginaseProlineAnticancer enzymeCacti floursEndophytesSubmerged fermentation

Identifiers

PMID36289148
OpenAlexW4307446636

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.