SynthesisSurgical endoscopy2023
Endoscopic ultrasound (EUS)-guided cholecystostomy versus percutaneous cholecystostomy (PTC) in the management of acute cholecystitis in patients unfit for surgery: a systematic review and meta-analysis.
Synthesis in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Endoscopic ultrasound-guided versus percutaneous transhepatic gallbladder drainage in surgically high-risk patients with acute cholecystitis: a systematic review and meta-analysis.Surgical endoscopy · 2026Pooled it
- Pooled it
- Technical Evolution, Clinical Application, and Outcomes of Endoscopic Transpapillary Gallbladder Drainage in Acute Cholecystitis: A Review.Journal of clinical medicine · 2026Review
- Endoscopic Ultrasound-Guided Gallbladder Drainage for Acute Cholecystitis in Billroth II Anatomy via Afferent Limb.ACG case reports journal · 2026Article
- Endoscopic-Ultrasound-Guided Gallbladder Drainage in Patients with Percutaneous Cholecystostomy Drain.Journal of clinical medicine · 2026Article
- Therapeutic Endoscopic Ultrasound in Biliopancreatic Disease.Journal of clinical medicine · 2026Review
- Outcomes of Endoscopic Ultrasound-Guided Gallbladder Drainage Using Lumen-Apposing Metal Stent Performed by Early Career Advanced Endoscopists: A Multicenter Study.Digestive diseases and sciences · 2026Article
- Endoscopic management of acute cholecystitis in high-risk surgical patients: A comprehensive review article.DEN open · 2026Review
- Endoscopic ultrasound-guided gallbladder drainage for bilirubin normalization in distal malignant biliary obstruction: A focused review.World journal of gastrointestinal endoscopy · 2026Review
- Interventional management of acute perforated cholecystitis: When is percutaneous transhepatic cholecystostomy a reasonable therapeutic option?World journal of gastrointestinal surgery · 2026Article
- The Effect of Lumen-Apposing Metal Stent (LAMS) in Acute Cholecystitis Unfit for Surgery: Good Tidings.Diagnostics (Basel, Switzerland) · 2025Review
- Clinical update on acute cholecystitis and biliary pancreatitis: between certainties and grey areas.EClinicalMedicine · 2024Review
- Peroral cholecystoscopy-guided interventions through a lumen-apposing metal stent after EUS-guided gallbladder drainage: proof-of-concept study in a swine model.iGIE : innovation, investigation and insights · 2024Article
- Intrathoracic cholecystitis managed with endoscopic gallbladder drainage.iGIE : innovation, investigation and insights · 2024Article
- EUS-guided gallbladder drainage in acute cholecystitis: long-term problems with surgical approach.Gut · 2024Article
- Ultrasound-Guided Interventions in the Biliary System.Diagnostics (Basel, Switzerland) · 2024Review
- The past, present, and future of endoscopic management for biliary strictures: technological innovations and stent advancements.Frontiers in medicine · 2024Review
- A review of endoscopic ultrasound-guided gallbladder drainage and gastroenterostomy: assisted approaches and comparison with alternative techniques.Therapeutic advances in gastroenterology · 2024Review
- Cesena guidelines: WSES consensus statement on laparoscopic-first approach to general surgery emergencies and abdominal trauma.World journal of emergency surgery : WJES · 2023Article
- The Use of a New Dedicated Electrocautery Lumen-Apposing Metal Stent for Gallbladder Drainage in Patients with Acute Cholecystitis.Diagnostics (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimSurgical cholecystectomy is the gold standard strategy for the management of acute cholecystitis (AC). However, some patients are considered unfit for surgery due to certain comorbid conditions. As such, we aimed to compare less invasive treatment strategies such as endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) and percutaneous gallbladder drainage (PT-GBD) for the management of patients with AC who are suboptimal candidates for surgical cholecystectomy.
methodsA comprehensive search of multiple electronic databases was performed to identify all the studies comparing EUS-GBD versus PT-GBD for patients with AC who were unfit for surgery. A subgroup analysis was also performed for comparison of the group undergoing drainage via cautery-enhanced lumen-apposing metal stents (LAMS) versus PT-GBD. The outcomes included technical and clinical success, adverse events (AEs), recurrent cholecystitis, reintervention, and hospital readmission.
resultsEleven studies including 1155 patients were included in the statistical analysis. There was no difference between PT-GBD and EUS-GBD in all the evaluated outcomes. On the subgroup analysis, the endoscopic approach with cautery-enhanced LAMS was associated with lower rates of adverse events (RD = - 0.33 (95% CI - 0.52 to - 0.14; p = 0.0006), recurrent cholecystitis (- 0.05 RD (95% CI - 0.09 to - 0.02; p = 0.02), and hospital readmission (- 0.36 RD (95% CI-0.70 to - 0.03; p = 0.03) when compared to PT-GBD. All other outcomes were similar in the subgroup analyses.
conclusionsEUS-GBD using cautery-enhanced LAMS is superior to PT-GBD in terms of safety profile, recurrent cholecystitis, and hospital readmission rates in the management of patients with acute cholecystitis who are suboptimal candidates for cholecystectomy. However, when cautery-enhanced LAMS are not used, the outcomes of EUS-GBD and PT-GBD are similar. Thus, EUS-GBD with cautery-enhanced LAMS should be considered the preferable approach for gallbladder drainage for this challenging population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.