Evidence map›Paper›PMID 36289066›Full record

ArticleApplied microbiology and biotechnology2022

Ethylene glycol metabolism in the poly(ethylene terephthalate)-degrading bacterium Ideonella sakaiensis.

Shin-Ichi Hachisuka, Jia Fong Chong, Tsuyoshi Fujiwara, Akiyo Takayama, Yumiko Kawakami, Shosuke Yoshida

Abstract read
PubMed Publisher
In one paragraph

Article in Applied microbiology and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Transcriptome data sets ofMicrobiology resource announcements · 2026
    Article
  4. Multicriteria evaluation of ethylene glycol assimilation pathways.Journal of industrial microbiology & biotechnology · 2026
    Article
  5. Microbial plastic degradation: enzymes, pathways, challenges, and perspectives.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. The catabolism of ethylene glycol byApplied and environmental microbiology · 2024
    Article
  15. Novel aspects of ethylene glycol catabolism.Applied microbiology and biotechnology · 2024
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shin-Ichi HachisukaInstitute for Research Initiatives, Division for Research Strategy, Nara Institute of Science and Technology, 8916-5 Takayama-cho, Ikoma, Nara, 630-0192, Japan.
Jia Fong ChongGraduate School of Biological Science, Nara Institute of Science and Technology, 8916-5 Takayama-cho, Ikoma, Nara, 630-0192, Japan.
Tsuyoshi FujiwaraGraduate School of Biological Science, Nara Institute of Science and Technology, 8916-5 Takayama-cho, Ikoma, Nara, 630-0192, Japan.
Akiyo TakayamaGraduate School of Biological Science, Nara Institute of Science and Technology, 8916-5 Takayama-cho, Ikoma, Nara, 630-0192, Japan.
Yumiko KawakamiInstitute for Research Initiatives, Division for Research Strategy, Nara Institute of Science and Technology, 8916-5 Takayama-cho, Ikoma, Nara, 630-0192, Japan.
Shosuke YoshidaInstitute for Research Initiatives, Division for Research Strategy, Nara Institute of Science and Technology, 8916-5 Takayama-cho, Ikoma, Nara, 630-0192, Japan. ssk-yoshida@bs.naist.jp.ORCID http://orcid.org/0000-0002-2831-9027
Nara Institute of Science and Technology · JP

Funding

Japan Science and Technology Agency 1126326Japan Society for the Promotion of Science 17H03794Japan Society for the Promotion of Science 19K15735Japan Society for the Promotion of Science 21H02104MEXT 16810109
6 · The paper itself

Abstract

Poly(ethylene terephthalate) (PET)-degrading bacterium Ideonella sakaiensis produces hydrolytic enzymes that convert PET, via mono(2-hydroxyethyl) terephthalate (MHET), into the monomeric compounds, terephthalic acid (TPA), and ethylene glycol (EG). Understanding PET metabolism is critical if this bacterium is to be engineered for bioremediation and biorecycling. TPA uptake and catabolism in I. sakaiensis have previously been studied, but EG metabolism remains largely unexplored despite its importance. First, we identified two alcohol dehydrogenases (IsPedE and IsPedH) and one aldehyde dehydrogenase (IsPedI) in I. sakaiensis as the homologs of EG metabolic enzymes in Pseudomonas putida KT2440. IsPedE and IsPedH exhibited EG dehydrogenase activities with Ca

Indexed as

Ethylene GlycolPolyethylene TerephthalatesAcetaldehydeBurkholderialesEthylenesHydrolasesOxidoreductasesPhthalic AcidsAcetaldehydeEthylene GlycolEthylenesglycolaldehydeHydrolasesOxidoreductasesPhthalic AcidsPolyethylene Terephthalatesterephthalic acidAlcohol dehydrogenaseAldehyde dehydrogenaseEthylene glycol metabolismIdeonella sakaiensisPoly(ethylene terephthalate)

Identifiers

PMID36289066
OpenAlexW4307428024

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.