ArticleNeurology(R) neuroimmunology & neuroinflammation2023
Early-Stage Contactin-Associated Protein-like 2 Limbic Encephalitis: Clues for Diagnosis.
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Article in Neurology(R) neuroimmunology & neuroinflammation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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17citing papers in PubMed, 2 pooled it
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17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Investigating health related quality of life and clinical measures in autoimmune encephalitis: a systematic review.Orphanet journal of rare diseases · 2025Pooled it
- Retrograde Amnesia in LGI1 and CASPR2 Limbic Encephalitis: Two Case Reports and a Systematic Literature Review.European journal of neurology · 2025Pooled it
- Long-Term Outcomes in Autoimmune Encephalitis: A Nationwide, Clinical Study in Denmark.Neurology(R) neuroimmunology & neuroinflammation · 2026Article
- CASPR2 antibody-related neurological syndromes in children: three cases report and literature review.BMC pediatrics · 2026Review
- High Relapse Rate in Anti-CASPR2 Disease: Implications for Prolonged Immunotherapy.Neurology(R) neuroimmunology & neuroinflammation · 2026Observational
- Brain atrophy in autoimmune encephalitis: epidemiology, pathophysiology, clinical manifestations, treatment, and prognosis-an update.Journal of neurology · 2025Review
- Progress and challenges in sporadic late-onset cerebellar ataxias.Nature reviews. Neurology · 2025Review
- Differential Diagnosis of Infectious Versus Autoimmune Encephalitis Using Artificial Intelligence-Based Modeling.Journal of clinical medicine · 2025Article
- Autoimmune encephalitis.Nature reviews. Disease primers · 2025Review
- Neurodegeneration and the immune system: lessons from autoimmune encephalitis.Journal of neurology · 2025Review
- Homer-3 antibody in autoimmune cerebellar syndromes: a potentially treatable mimic of MSA-C - A review.Frontiers in immunology · 2025Review
- Recent advances in autoimmune encephalitis.Arquivos de neuro-psiquiatria · 2024Review
- Human cerebrospinal fluid monoclonal CASPR2 autoantibodies induce changes in electrophysiology, functional MRI, and behavior in rodent models.Brain, behavior, and immunity · 2024Article
- Emerging Biomarkers for the Early Detection of Autoimmune Encephalitis: A Narrative Review.Cureus · 2024Review
- Outcome and Sequelae of Autoimmune Encephalitis.Journal of clinical neurology (Seoul, Korea) · 2024Review
- Paraneoplastic Neurological Syndromes of the Central Nervous System: Pathophysiology, Diagnosis, and Treatment.Biomedicines · 2023Review
- Seizures, Epilepsy, and NORSE Secondary to Autoimmune Encephalitis: A Practical Guide for Clinicians.Biomedicines · 2022Review
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Authors and funding
13 authors at 5 institutions in 1 country.
Jeanne BenoitFrom the French Reference Center on Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Hospices Civils de Lyon; Synaptopathies and Autoantibodies (SynatAc) Team (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Institut NeuroMyoGène, MELIS, INSERM U1314/CNRS UMR 5284, Université Claude Bernard Lyon 1; Epileptology-EEG Department (J.B.), Neurology, Pasteur2 Hospital, University Hospitals of Nice; Côte d'Azur University (J.B.), UR2CA, URRIS, Pasteur2 Hospital, University Hospitals of Nice; Department of Functional Neurology and Epileptology (D.G., S.R.), Hospices Civils de Lyon, France; European Network for Rare and Complex Epilepsies (EPICARE) (D.G., S.R.); Service de Neurologie 2-Mazarin (A.A., D.P.), Hôpitaux Universitaires La Pitié-Salpêtrière-Charles Foix, APHP; Inserm U1127 CNRS UMR 7225 (A.A., D.P.), Institut Du Cerveau et de la Moelle épinière, ICM, Université Pierre-et-Marie-Curie, Sorbonne Universités, Paris; and Lyon's Neuroscience Research Center (S.R.), INSERM U1028/CNRS UMR 5292; Université Lyon 1 Claude Bernard, France.
Sergio Muñiz-CastrilloFrom the French Reference Center on Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Hospices Civils de Lyon; Synaptopathies and Autoantibodies (SynatAc) Team (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Institut NeuroMyoGène, MELIS, INSERM U1314/CNRS UMR 5284, Université Claude Bernard Lyon 1; Epileptology-EEG Department (J.B.), Neurology, Pasteur2 Hospital, University Hospitals of Nice; Côte d'Azur University (J.B.), UR2CA, URRIS, Pasteur2 Hospital, University Hospitals of Nice; Department of Functional Neurology and Epileptology (D.G., S.R.), Hospices Civils de Lyon, France; European Network for Rare and Complex Epilepsies (EPICARE) (D.G., S.R.); Service de Neurologie 2-Mazarin (A.A., D.P.), Hôpitaux Universitaires La Pitié-Salpêtrière-Charles Foix, APHP; Inserm U1127 CNRS UMR 7225 (A.A., D.P.), Institut Du Cerveau et de la Moelle épinière, ICM, Université Pierre-et-Marie-Curie, Sorbonne Universités, Paris; and Lyon's Neuroscience Research Center (S.R.), INSERM U1028/CNRS UMR 5292; Université Lyon 1 Claude Bernard, France.
Alberto VogrigFrom the French Reference Center on Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Hospices Civils de Lyon; Synaptopathies and Autoantibodies (SynatAc) Team (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Institut NeuroMyoGène, MELIS, INSERM U1314/CNRS UMR 5284, Université Claude Bernard Lyon 1; Epileptology-EEG Department (J.B.), Neurology, Pasteur2 Hospital, University Hospitals of Nice; Côte d'Azur University (J.B.), UR2CA, URRIS, Pasteur2 Hospital, University Hospitals of Nice; Department of Functional Neurology and Epileptology (D.G., S.R.), Hospices Civils de Lyon, France; European Network for Rare and Complex Epilepsies (EPICARE) (D.G., S.R.); Service de Neurologie 2-Mazarin (A.A., D.P.), Hôpitaux Universitaires La Pitié-Salpêtrière-Charles Foix, APHP; Inserm U1127 CNRS UMR 7225 (A.A., D.P.), Institut Du Cerveau et de la Moelle épinière, ICM, Université Pierre-et-Marie-Curie, Sorbonne Universités, Paris; and Lyon's Neuroscience Research Center (S.R.), INSERM U1028/CNRS UMR 5292; Université Lyon 1 Claude Bernard, France.
Antonio FarinaFrom the French Reference Center on Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Hospices Civils de Lyon; Synaptopathies and Autoantibodies (SynatAc) Team (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Institut NeuroMyoGène, MELIS, INSERM U1314/CNRS UMR 5284, Université Claude Bernard Lyon 1; Epileptology-EEG Department (J.B.), Neurology, Pasteur2 Hospital, University Hospitals of Nice; Côte d'Azur University (J.B.), UR2CA, URRIS, Pasteur2 Hospital, University Hospitals of Nice; Department of Functional Neurology and Epileptology (D.G., S.R.), Hospices Civils de Lyon, France; European Network for Rare and Complex Epilepsies (EPICARE) (D.G., S.R.); Service de Neurologie 2-Mazarin (A.A., D.P.), Hôpitaux Universitaires La Pitié-Salpêtrière-Charles Foix, APHP; Inserm U1127 CNRS UMR 7225 (A.A., D.P.), Institut Du Cerveau et de la Moelle épinière, ICM, Université Pierre-et-Marie-Curie, Sorbonne Universités, Paris; and Lyon's Neuroscience Research Center (S.R.), INSERM U1028/CNRS UMR 5292; Université Lyon 1 Claude Bernard, France.
Anne-Laurie PintoFrom the French Reference Center on Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Hospices Civils de Lyon; Synaptopathies and Autoantibodies (SynatAc) Team (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Institut NeuroMyoGène, MELIS, INSERM U1314/CNRS UMR 5284, Université Claude Bernard Lyon 1; Epileptology-EEG Department (J.B.), Neurology, Pasteur2 Hospital, University Hospitals of Nice; Côte d'Azur University (J.B.), UR2CA, URRIS, Pasteur2 Hospital, University Hospitals of Nice; Department of Functional Neurology and Epileptology (D.G., S.R.), Hospices Civils de Lyon, France; European Network for Rare and Complex Epilepsies (EPICARE) (D.G., S.R.); Service de Neurologie 2-Mazarin (A.A., D.P.), Hôpitaux Universitaires La Pitié-Salpêtrière-Charles Foix, APHP; Inserm U1127 CNRS UMR 7225 (A.A., D.P.), Institut Du Cerveau et de la Moelle épinière, ICM, Université Pierre-et-Marie-Curie, Sorbonne Universités, Paris; and Lyon's Neuroscience Research Center (S.R.), INSERM U1028/CNRS UMR 5292; Université Lyon 1 Claude Bernard, France.
Geraldine PicardFrom the French Reference Center on Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Hospices Civils de Lyon; Synaptopathies and Autoantibodies (SynatAc) Team (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Institut NeuroMyoGène, MELIS, INSERM U1314/CNRS UMR 5284, Université Claude Bernard Lyon 1; Epileptology-EEG Department (J.B.), Neurology, Pasteur2 Hospital, University Hospitals of Nice; Côte d'Azur University (J.B.), UR2CA, URRIS, Pasteur2 Hospital, University Hospitals of Nice; Department of Functional Neurology and Epileptology (D.G., S.R.), Hospices Civils de Lyon, France; European Network for Rare and Complex Epilepsies (EPICARE) (D.G., S.R.); Service de Neurologie 2-Mazarin (A.A., D.P.), Hôpitaux Universitaires La Pitié-Salpêtrière-Charles Foix, APHP; Inserm U1127 CNRS UMR 7225 (A.A., D.P.), Institut Du Cerveau et de la Moelle épinière, ICM, Université Pierre-et-Marie-Curie, Sorbonne Universités, Paris; and Lyon's Neuroscience Research Center (S.R.), INSERM U1028/CNRS UMR 5292; Université Lyon 1 Claude Bernard, France.
Veronique RogemondFrom the French Reference Center on Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Hospices Civils de Lyon; Synaptopathies and Autoantibodies (SynatAc) Team (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Institut NeuroMyoGène, MELIS, INSERM U1314/CNRS UMR 5284, Université Claude Bernard Lyon 1; Epileptology-EEG Department (J.B.), Neurology, Pasteur2 Hospital, University Hospitals of Nice; Côte d'Azur University (J.B.), UR2CA, URRIS, Pasteur2 Hospital, University Hospitals of Nice; Department of Functional Neurology and Epileptology (D.G., S.R.), Hospices Civils de Lyon, France; European Network for Rare and Complex Epilepsies (EPICARE) (D.G., S.R.); Service de Neurologie 2-Mazarin (A.A., D.P.), Hôpitaux Universitaires La Pitié-Salpêtrière-Charles Foix, APHP; Inserm U1127 CNRS UMR 7225 (A.A., D.P.), Institut Du Cerveau et de la Moelle épinière, ICM, Université Pierre-et-Marie-Curie, Sorbonne Universités, Paris; and Lyon's Neuroscience Research Center (S.R.), INSERM U1028/CNRS UMR 5292; Université Lyon 1 Claude Bernard, France.
Deborah GueryFrom the French Reference Center on Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Hospices Civils de Lyon; Synaptopathies and Autoantibodies (SynatAc) Team (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Institut NeuroMyoGène, MELIS, INSERM U1314/CNRS UMR 5284, Université Claude Bernard Lyon 1; Epileptology-EEG Department (J.B.), Neurology, Pasteur2 Hospital, University Hospitals of Nice; Côte d'Azur University (J.B.), UR2CA, URRIS, Pasteur2 Hospital, University Hospitals of Nice; Department of Functional Neurology and Epileptology (D.G., S.R.), Hospices Civils de Lyon, France; European Network for Rare and Complex Epilepsies (EPICARE) (D.G., S.R.); Service de Neurologie 2-Mazarin (A.A., D.P.), Hôpitaux Universitaires La Pitié-Salpêtrière-Charles Foix, APHP; Inserm U1127 CNRS UMR 7225 (A.A., D.P.), Institut Du Cerveau et de la Moelle épinière, ICM, Université Pierre-et-Marie-Curie, Sorbonne Universités, Paris; and Lyon's Neuroscience Research Center (S.R.), INSERM U1028/CNRS UMR 5292; Université Lyon 1 Claude Bernard, France.
Agusti AlentornFrom the French Reference Center on Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Hospices Civils de Lyon; Synaptopathies and Autoantibodies (SynatAc) Team (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Institut NeuroMyoGène, MELIS, INSERM U1314/CNRS UMR 5284, Université Claude Bernard Lyon 1; Epileptology-EEG Department (J.B.), Neurology, Pasteur2 Hospital, University Hospitals of Nice; Côte d'Azur University (J.B.), UR2CA, URRIS, Pasteur2 Hospital, University Hospitals of Nice; Department of Functional Neurology and Epileptology (D.G., S.R.), Hospices Civils de Lyon, France; European Network for Rare and Complex Epilepsies (EPICARE) (D.G., S.R.); Service de Neurologie 2-Mazarin (A.A., D.P.), Hôpitaux Universitaires La Pitié-Salpêtrière-Charles Foix, APHP; Inserm U1127 CNRS UMR 7225 (A.A., D.P.), Institut Du Cerveau et de la Moelle épinière, ICM, Université Pierre-et-Marie-Curie, Sorbonne Universités, Paris; and Lyon's Neuroscience Research Center (S.R.), INSERM U1028/CNRS UMR 5292; Université Lyon 1 Claude Bernard, France.
Dimitri PsimarasFrom the French Reference Center on Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Hospices Civils de Lyon; Synaptopathies and Autoantibodies (SynatAc) Team (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Institut NeuroMyoGène, MELIS, INSERM U1314/CNRS UMR 5284, Université Claude Bernard Lyon 1; Epileptology-EEG Department (J.B.), Neurology, Pasteur2 Hospital, University Hospitals of Nice; Côte d'Azur University (J.B.), UR2CA, URRIS, Pasteur2 Hospital, University Hospitals of Nice; Department of Functional Neurology and Epileptology (D.G., S.R.), Hospices Civils de Lyon, France; European Network for Rare and Complex Epilepsies (EPICARE) (D.G., S.R.); Service de Neurologie 2-Mazarin (A.A., D.P.), Hôpitaux Universitaires La Pitié-Salpêtrière-Charles Foix, APHP; Inserm U1127 CNRS UMR 7225 (A.A., D.P.), Institut Du Cerveau et de la Moelle épinière, ICM, Université Pierre-et-Marie-Curie, Sorbonne Universités, Paris; and Lyon's Neuroscience Research Center (S.R.), INSERM U1028/CNRS UMR 5292; Université Lyon 1 Claude Bernard, France.
Sylvain RheimsFrom the French Reference Center on Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Hospices Civils de Lyon; Synaptopathies and Autoantibodies (SynatAc) Team (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Institut NeuroMyoGène, MELIS, INSERM U1314/CNRS UMR 5284, Université Claude Bernard Lyon 1; Epileptology-EEG Department (J.B.), Neurology, Pasteur2 Hospital, University Hospitals of Nice; Côte d'Azur University (J.B.), UR2CA, URRIS, Pasteur2 Hospital, University Hospitals of Nice; Department of Functional Neurology and Epileptology (D.G., S.R.), Hospices Civils de Lyon, France; European Network for Rare and Complex Epilepsies (EPICARE) (D.G., S.R.); Service de Neurologie 2-Mazarin (A.A., D.P.), Hôpitaux Universitaires La Pitié-Salpêtrière-Charles Foix, APHP; Inserm U1127 CNRS UMR 7225 (A.A., D.P.), Institut Du Cerveau et de la Moelle épinière, ICM, Université Pierre-et-Marie-Curie, Sorbonne Universités, Paris; and Lyon's Neuroscience Research Center (S.R.), INSERM U1028/CNRS UMR 5292; Université Lyon 1 Claude Bernard, France.
Jérôme HonnoratFrom the French Reference Center on Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Hospices Civils de Lyon; Synaptopathies and Autoantibodies (SynatAc) Team (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Institut NeuroMyoGène, MELIS, INSERM U1314/CNRS UMR 5284, Université Claude Bernard Lyon 1; Epileptology-EEG Department (J.B.), Neurology, Pasteur2 Hospital, University Hospitals of Nice; Côte d'Azur University (J.B.), UR2CA, URRIS, Pasteur2 Hospital, University Hospitals of Nice; Department of Functional Neurology and Epileptology (D.G., S.R.), Hospices Civils de Lyon, France; European Network for Rare and Complex Epilepsies (EPICARE) (D.G., S.R.); Service de Neurologie 2-Mazarin (A.A., D.P.), Hôpitaux Universitaires La Pitié-Salpêtrière-Charles Foix, APHP; Inserm U1127 CNRS UMR 7225 (A.A., D.P.), Institut Du Cerveau et de la Moelle épinière, ICM, Université Pierre-et-Marie-Curie, Sorbonne Universités, Paris; and Lyon's Neuroscience Research Center (S.R.), INSERM U1028/CNRS UMR 5292; Université Lyon 1 Claude Bernard, France.
Bastien JoubertFrom the French Reference Center on Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Hospices Civils de Lyon; Synaptopathies and Autoantibodies (SynatAc) Team (J.B., S.M.-C., A.V., A.F., A.-L.P., G.P., V.R., J.H., B.J.), Institut NeuroMyoGène, MELIS, INSERM U1314/CNRS UMR 5284, Université Claude Bernard Lyon 1; Epileptology-EEG Department (J.B.), Neurology, Pasteur2 Hospital, University Hospitals of Nice; Côte d'Azur University (J.B.), UR2CA, URRIS, Pasteur2 Hospital, University Hospitals of Nice; Department of Functional Neurology and Epileptology (D.G., S.R.), Hospices Civils de Lyon, France; European Network for Rare and Complex Epilepsies (EPICARE) (D.G., S.R.); Service de Neurologie 2-Mazarin (A.A., D.P.), Hôpitaux Universitaires La Pitié-Salpêtrière-Charles Foix, APHP; Inserm U1127 CNRS UMR 7225 (A.A., D.P.), Institut Du Cerveau et de la Moelle épinière, ICM, Université Pierre-et-Marie-Curie, Sorbonne Universités, Paris; and Lyon's Neuroscience Research Center (S.R.), INSERM U1028/CNRS UMR 5292; Université Lyon 1 Claude Bernard, France. bastien.joubert@chu-lyon.fr.
Hôpital Pasteur · FRCentre de Recherche en Neurosciences de Lyon · FRHospices Civils de Lyon · FRInserm · FRCentre National de la Recherche Scientifique · FR
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesPrevious studies suggested that autoimmune limbic encephalitis with antibodies against contactin-associated protein-like 2 (CASPR2-encephalitis) is clinically heterogeneous and progresses slowly, preventing its early recognition. We aimed to describe the onset and progression of CASPR2-encephalitis and to assess long-term outcomes.
methodsWe retrospectively analyzed the medical records of all patients whose CSF tested positive for anti-CASPR2 antibodies in our center between 2006 and 2020. Standardized telephone interviews of all available patients and relatives were conducted, assessing long-term functional independence using the Functional Activity Questionnaire (FAQ) and quality of life using the 36-Item Short-Form Survey (SF36).
resultsForty-eight patients were included (98% males; median age 64 years), and 35 participated in telephone interviews (73%). At onset, 81% had at least 1 neurologic symptom among the following: limbic (54%), peripheral nerve hyperexcitability (PNH; 21%), and/or cerebellar symptoms (17%). Most of the patients (75%) had initially symptoms of only one of these categories. Limbic symptoms at onset included mostly seizures (33%), while memory disturbances were less frequent (10%). PNH signs were mostly neuropathic pain (9/10 patients). Other symptoms seen at onset included asthenia (33%), mood disorders (25%), and insomnia (21%); 19% of patients did not show any limbic, peripheral, or cerebellar symptom at onset but only asthenia (15%), mood disorders (6%), weight loss (8%), dysautonomia (4%), and/or insomnia (2%). The peak of the disease was attained in median 16.7 months after onset. Over the study period (median follow-up, 58.8 months, range 10.6-189.1), 77% of patients developed ≥3 core CASPR2 symptoms and 42% fulfilled the diagnostic criteria for autoimmune limbic encephalitis, although all patients ultimately developed limbic symptoms. At the last visit, most interviewed patients (28/35 patients, 80%; median, 5 years after onset) had recovered functional independence (FAQ <9) while only the vitality subscore of the SF36 was lower than normative data (mean 49.9 vs 58.0, DISCUSSION: CASPR2-encephalitis has a progressive course and is highly heterogeneous at the early stage. In men older than 50 years, otherwise unexplained seizures, cerebellar ataxia, and/or neuropathic pain are suggestive of early-stage CASPR2-encephalitis, especially if they coincide with recent asthenia, mood disorders, or insomnia.
Indexed as
EncephalitisLimbic EncephalitisNeuralgiaSleep Initiation and Maintenance DisordersAstheniaAutoantibodiesAutoimmune DiseasesContactinsFemaleHumansMaleMembrane ProteinsMiddle AgedNerve Tissue ProteinsQuality of LifeRetrospective StudiesAutoantibodiesContactinsMembrane ProteinsNerve Tissue Proteins
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