Evidence map›Paper›PMID 36288382›Full record

ArticlePloS one2022

Chemical and physical restraint use during acute care hospitalization of older adults: A retrospective cohort study and time series analysis.

Aaron Jones, Zahra Goodarzi, Justin Lee, Richard Norman, Eric Wong, Monidipa Dasgupta, Barbara Liu, Jennifer Watt

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Prevalence of chemical restraint use in hospital care: a consensus and cross-sectional study.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2026
    Article
  3. Article
  4. Delirium and Coronavirus Disease 2019: Looking Back, Moving Forward.Critical care nursing clinics of North America · 2024
    Review
  5. Nursing Ethical Decision Making on Adult Physical Restraint: A Scoping Review.International journal of environmental research and public health · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Aaron JonesDepartment of Health Research Methods, Evidence, and Impact, McMaster University Hamilton, Hamilton, Ontario, Canada.ORCID 0000-0002-6282-3614
Zahra GoodarziDivision of Geriatric Medicine, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.
Justin LeeDivision of Geriatric Medicine, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Richard NormanDivision of Geriatric Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Eric WongDivision of Geriatric Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Monidipa DasguptaDivision of Geriatric Medicine, Department of Medicine, Western University, London, Ontario, Canada.
Barbara LiuDivision of Geriatric Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Jennifer WattICES, Toronto, Ontario, Canada.ORCID 0000-0002-5296-6013
St. Michael's Hospital · CAUniversity of Toronto · CAInstitute for Clinical Evaluative Sciences · CAMcMaster University · CAUniversity of Calgary · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChemical and physical restraints are associated with harm in older adults, but our understanding of their use during acute care hospitalizations is limited.

objectivesTo (1) describe restraint use during acute care hospitalizations of older adults at the onset of the COVID-19 pandemic compared to pre-pandemic levels and (2) describe between-hospital variability in restraint use.

designRetrospective cohort study with a time series analysis.

participantsAcute care hospital inpatients, aged 65 years or older, who were discharged from one of four Alberta hospitals or six Ontario hospitals in Canada, between November 1, 2019, and June 30, 2020. MAIN MEASURES: We used autoregressive linear models with restricted cubic splines to compare proportions of chemical restraint (that is, psychotropic medications, namely antipsychotics, benzodiazepines, and trazodone) and physical restraint (e.g., mittens) use immediately after the onset of the COVID-19 pandemic with pre-pandemic levels. We describe between-hospital variability in restraint use using intraclass correlation coefficients (ICC) and median odds ratios (OR). KEY

resultsWe included 71,004 hospitalizations. Adjusted for the prevalence of dementia and psychotic disorders, chemical restraint use increased in Ontario hospitals from a pre-pandemic average of 27.1% to 30.8% (p<0.001) before returning to pre-pandemic levels within eight weeks. Physical restraint orders in Ontario increased from 5.9% to 8.3% (p = 0.012) and remained elevated at eight weeks. No significant changes in restraint use were observed in Alberta. There was moderate between-hospital variability in chemical restraint use (ICC 0.041 and median OR 1.43). Variability in physical restraint use was higher (ICC 0.11 and median OR 1.83).

conclusionsThe COVID-19 pandemic impacted in-hospital use of chemical and physical restraints among older adults in Ontario but not Alberta. Substantial differences in chemical and physical restraint use by region and hospital suggests there are opportunities to improve best practices in geriatric care. Future research must support implementation of evidence-informed interventions that standardize appropriate restraint use.

Indexed as

COVID-19TrazodoneAgedAlbertaBenzodiazepinesHospitalizationHumansPandemicsRestraint, PhysicalRetrospective StudiesTime FactorsBenzodiazepinesTrazodone

Identifiers

PMID36288382
PMCPMC9604990
OpenAlexW4307313472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.