Evidence map›Paper›PMID 36287965›Full record

ArticleToxins2022

Evaluation of a Novel Synthetic Peptide Derived from Cytolytic Mycotoxin Candidalysin.

Pedro Henrique de Oliveira Cardoso, Ana Paula de Araújo Boleti, Patrícia Souza E Silva, Lincoln Takashi Hota Mukoyama, Alexya Sandim Guindo, Luiz Filipe Ramalho Nunes de Moraes, Caio Fernando Ramalho de Oliveira, Maria Ligia Rodrigues Macedo, Cristiano Marcelo Espínola Carvalho, Alinne Pereira de Castro and 1 more

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Pedro Henrique de Oliveira CardosoS-Inova Biotech, Programa de Pós-graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande 79117-900, Mato Grosso do Sul, Brazil.ORCID 0000-0002-2872-3767
Ana Paula de Araújo BoletiS-Inova Biotech, Programa de Pós-graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande 79117-900, Mato Grosso do Sul, Brazil.
Patrícia Souza E SilvaS-Inova Biotech, Programa de Pós-graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande 79117-900, Mato Grosso do Sul, Brazil.
Lincoln Takashi Hota MukoyamaS-Inova Biotech, Programa de Pós-graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande 79117-900, Mato Grosso do Sul, Brazil.ORCID 0000-0002-6977-3920
Alexya Sandim GuindoS-Inova Biotech, Programa de Pós-graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande 79117-900, Mato Grosso do Sul, Brazil.
Luiz Filipe Ramalho Nunes de MoraesS-Inova Biotech, Programa de Pós-graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande 79117-900, Mato Grosso do Sul, Brazil.ORCID 0000-0003-0716-5062
Caio Fernando Ramalho de OliveiraLaboratório de Purificação de Proteínas e suas Funções Biológicas, Unidade de Tecnologia de Alimentos e da Saúde Pública, Universidade Federal de Mato Grosso do Sul, Campo Grande 79070-900, Mato Grosso do Sul, Brazil.ORCID 0000-0002-3867-9528
Maria Ligia Rodrigues MacedoLaboratório de Purificação de Proteínas e suas Funções Biológicas, Unidade de Tecnologia de Alimentos e da Saúde Pública, Universidade Federal de Mato Grosso do Sul, Campo Grande 79070-900, Mato Grosso do Sul, Brazil.ORCID 0000-0001-6969-6307
Cristiano Marcelo Espínola CarvalhoS-Inova Biotech, Programa de Pós-graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande 79117-900, Mato Grosso do Sul, Brazil.
Alinne Pereira de CastroS-Inova Biotech, Programa de Pós-graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande 79117-900, Mato Grosso do Sul, Brazil.
Ludovico MiglioloS-Inova Biotech, Programa de Pós-graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande 79117-900, Mato Grosso do Sul, Brazil.ORCID 0000-0002-6606-2189
Universidade Católica Dom Bosco · BRUniversidade Federal de Mato Grosso do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The importance of neuroinflammation in neurology is becoming increasingly apparent. In addition to neuroinflammatory diseases such as multiple sclerosis, the role of neuroinflammation has been identified in many non-inflammatory neurological disorders such as stroke, epilepsy, and cancer. The immune response within the brain involves the presence of CNS resident cells; mainly glial cells, such as microglia, the CNS resident macrophages. We evaluated the peptide Ca-MAP1 bioinspired on the

Indexed as

Escherichia coliMycotoxinsAnti-Bacterial AgentsCandida albicansFungal ProteinsMicrobial Sensitivity TestsNitratesPeptidesPseudomonas aeruginosaAnti-Bacterial AgentsECE1 protein, Candida albicansFungal ProteinsMycotoxinsNitratesPeptidesCandida albicansdrug designmultiactivity peptideneuroinflammationpeptide toxin

Identifiers

PMID36287965
PMCPMC9610734
OpenAlexW4304783966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.