Evidence map›Paper›PMID 36287949›Full record

ArticleToxins2022

Tardive Oromandibular Dystonia Induced by Trazodone: A Clinical Case and Management from the Perspective of the Dental Specialist.

Nicolás P Skarmeta, Giannina C Katzmann, Constanza Valdés, Dominique Gaedechens, Francisca C Montini

Open access · goldAbstract readCase Reports
In one paragraph

Article in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. The epidemiology and phenomenology of non-antipsychotic-induced dystonia: a hybrid systematic-narrative review.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Pooled it
  2. Article
  3. Trazodone-related oromandibular dyskinesia.Journal of family medicine and primary care · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nicolás P SkarmetaFacultad de Odontología, Universidad de los Andes, Santiago 7620001, Chile.
Giannina C KatzmannFacultad de Odontología, Universidad de los Andes, Santiago 7620001, Chile.
Constanza ValdésFacultad de Odontología, Universidad de los Andes, Santiago 7620001, Chile.
Dominique GaedechensOPH Clinic, Vitacura 7630000, Chile.
Francisca C MontiniFacultad de Odontología, Universidad de los Andes, Santiago 7620001, Chile.ORCID 0000-0002-8785-2673
Universidad de Los Andes, Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTardive Oromandibular Dystonia is an iatrogenic drug-induced movement form of extrapyramidal symptoms associated primarily with chronic consumption of dopamine receptor blocking agents. Tardive symptoms attributable to selective serotonin reuptake inhibitors antidepressants are far less prevalent. CLINICAL CASE: The authors will present a clinical case and management, from the dental specialist perspective, of a 55-year-old female patient who developed tardive oromandibular dystonia induced by Trazodone prescribed for sleep insomnia.

conclusionsTrazodone-induced oromandibular dystonia is extremely rare. Early identification and assessment of tardive symptoms are imperative for successful treatment. Trazodone should be prescribed with caution in patients taking other medications with the potential to cause tardive syndromes.

Indexed as

DystoniaDystonic DisordersTrazodoneFemaleHumansMiddle AgedReceptors, DopamineSelective Serotonin Reuptake InhibitorsReceptors, DopamineSelective Serotonin Reuptake InhibitorsTrazodonebotulinum toxinoromandibular dystoniatardive dystoniatrazodone

Identifiers

PMID36287949
PMCPMC9607571
OpenAlexW4304609818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.