Evidence map›Paper›PMID 36287935›Full record

ArticleToxins2022

Effects of Flexor Digitorum Longus Muscle Anatomical Structure on the Response to Botulinum Toxin Treatment in Patients with Post-Stroke Claw Foot Deformity.

Toru Takekawa, Kazushige Kobayashi, Naoki Yamada, Satoshi Takagi, Takatoshi Hara, Tomohide Kitajima, Tomoharu Sato, Hiroshi Sugihara, Kazuo Kinoshita, Masahiro Abo

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Toru TakekawaDepartment of Rehabilitation Medicine, The Jikei University School of Medicine, Tokyo 105-8461, Japan.ORCID 0000-0001-7077-4261
Kazushige KobayashiDepartment of Rehabilitation Medicine, The Jikei University School of Medicine, Tokyo 105-8461, Japan.ORCID 0000-0002-0573-1174
Naoki YamadaDepartment of Rehabilitation Medicine, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
Satoshi TakagiDepartment of Rehabilitation Medicine, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
Takatoshi HaraDepartment of Rehabilitation Medicine, The Jikei University School of Medicine, Tokyo 105-8461, Japan.ORCID 0000-0002-4153-168X
Tomohide KitajimaDepartment of Cerebrospinal Surgery, Medical Center Narita Hospital, Narita, Chiba 286-0845, Japan.
Tomoharu SatoMotoyama Rehabilitation Hospital, Kobe 658-0015, Hyogo, Japan.
Hiroshi SugiharaDepartment of Neurology, Kita-Kashiwa Rehabilitation General Hospital, Kashiwa, Chiba 277-0004, Japan.
Kazuo KinoshitaThe Jikei University Hospital, Tokyo 105-8471, Japan.
Masahiro AboDepartment of Rehabilitation Medicine, The Jikei University School of Medicine, Tokyo 105-8461, Japan.ORCID 0000-0001-6701-4974
Jikei University School of Medicine · JPHyogo Social Welfare Corporation · JPJapanese Red Cross Narita Hospital · JPKitakashiwa Rehabilitation General Hospital · JPThe Jikei University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: The purpose of this retrospective case-control study was to determine the relationship between the control of toe movements by flexor hallucis longus (FHL) and flexor digitorum longus (FDL) muscles and the response to treatment with botulinum toxin (BoNT) in post-stroke patients with claw toe. (2) Methods: Subjects with stroke-related leg paralysis/spasticity and claw toes received multiple injections of BoNT (onabotulinumtoxin A) into the FHL or FDL muscles. We investigated the relationship between the mode of transmission of FHL and FDL muscle tension to each toe (MCT) and treatment outcome using the data of 53 patients who received 124 injections with clinically recorded treatment outcome. We also dissected the potential variables that could determine the treatment outcome. (3) Results: The effectiveness of BoNT treatment was significantly altered by FDL-MCT (OR = 0.400, 95% CI = 0.162-0.987,

Indexed as

Botulinum Toxins, Type AFoot DeformitiesHammer Toe SyndromeCase-Control StudiesHumansMuscle, SkeletalRetrospective StudiesBotulinum Toxins, Type Aanatomic variationcerebrovascular disorderselectric stimulationflexor digitorum longusflexor hallucis longushammer toe syndromemuscle contraction

Identifiers

PMID36287935
PMCPMC9610091
OpenAlexW4298003686

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.