Evidence map›Paper›PMID 36287882›Full record

ArticleToxics2022

Biokinetics and Internal Dosimetry of Tritiated Steel Particles.

Rachel Smith, Michele Ellender, Chang Guo, Derek Hammond, Adam Laycock, Martin O Leonard, Matthew Wright, Michael Davidson, Véronique Malard, Mickaël Payet and 2 more

Abstract read
In one paragraph

Article in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rachel SmithRadiation Chemicals and Environmental Hazards, UK Health Security Agency, Harwell Campus, Didcot OX11 0RQ, UK.
Michele EllenderRadiation Chemicals and Environmental Hazards, UK Health Security Agency, Harwell Campus, Didcot OX11 0RQ, UK.
Chang GuoRadiation Chemicals and Environmental Hazards, UK Health Security Agency, Harwell Campus, Didcot OX11 0RQ, UK.ORCID 0000-0002-9662-1885
Derek HammondRadiation Chemicals and Environmental Hazards, UK Health Security Agency, Harwell Campus, Didcot OX11 0RQ, UK.
Adam LaycockRadiation Chemicals and Environmental Hazards, UK Health Security Agency, Harwell Campus, Didcot OX11 0RQ, UK.ORCID 0000-0001-9480-5149
Martin O LeonardRadiation Chemicals and Environmental Hazards, UK Health Security Agency, Harwell Campus, Didcot OX11 0RQ, UK.
Matthew WrightRadiation Chemicals and Environmental Hazards, UK Health Security Agency, Harwell Campus, Didcot OX11 0RQ, UK.
Michael DavidsonRadiation Chemicals and Environmental Hazards, UK Health Security Agency, Harwell Campus, Didcot OX11 0RQ, UK.
Véronique MalardBiosciences and Biotechnology Institute of Aix-Marseille (BIAM) (Aix-Marseille University, French Alternative Energies and Atomic Energy Commission (CEA), French National Centre for Scientific Research (CNRS)), 13108 Saint Paul-Lez-Durance, France.ORCID 0000-0002-0020-0518
Mickaël PayetInstitute for Magnetic Fusion Research (IRFM), French Alternative Energies and Atomic Energy Commission (CEA), 13108 Saint-Paul-lez-Durance, France.
Christian GrisoliaInstitute for Magnetic Fusion Research (IRFM), French Alternative Energies and Atomic Energy Commission (CEA), 13108 Saint-Paul-lez-Durance, France.ORCID 0000-0002-3038-9593
Eric BlanchardonInstitut de Radioprotection et de Sûreté Nucléaire (IRSN), 92260 Fontenay-aux-Roses, France.

Funding

Euratom Research and Training Programme 754586
6 · The paper itself

Abstract

Decommissioning fission and fusion facilities can result in the production of airborne particles containing tritium that could inadvertently be inhaled by workers directly involved in the operations, and potentially others, resulting in internal exposures to tritium. Of particular interest in this context, given the potentially large masses of material involved, is tritiated steel. The International Commission on Radiological Protection (ICRP) has recommended committed effective dose coefficients for inhalation of some tritiated materials, but not specifically for tritiated steel. The lack of a dose coefficient for tritiated steel is a concern given the potential importance of the material. To address this knowledge gap, a "dissolution" study, in vivo biokinetic study in a rodent model (1 MBq intratracheal instillation, 3-month follow-up) and associated state-of-the-art modelling were undertaken to derive dose coefficients for model tritiated steel particles. A committed effective dose coefficient for the inhalation of 3.3 × 10

Indexed as

biokineticsdissolutiondose coefficientsdosimetryrattritiated steel particlestritium

Identifiers

PMID36287882
PMCPMC9607624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.