Evidence map›Paper›PMID 36287839›Full record

ArticleToxics2022

Evaluation of Skin Irritation of Acids Commonly Used in Cleaners in 3D-Reconstructed Human Epidermis Model, KeraSkin

Jee-Hyun Hwang, Seungmi Lee, Ho Geon Lee, Dalwoong Choi, Kyung-Min Lim

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Preparation and Investigation ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Anti-Inflammatory Activity of Compounds Isolated fromInternational journal of molecular sciences · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jee-Hyun HwangCollege of Pharmacy, Ewha Womans University, Seoul 03760, Korea.
Seungmi LeeCollege of Pharmacy, Ewha Womans University, Seoul 03760, Korea.
Ho Geon LeeTransdisciplinary Major in Learning Health Systems, Department of Health and Safety Convergence Science, Korea University, Seoul 02481, Korea.
Dalwoong ChoiTransdisciplinary Major in Learning Health Systems, Department of Health and Safety Convergence Science, Korea University, Seoul 02481, Korea.
Kyung-Min LimCollege of Pharmacy, Ewha Womans University, Seoul 03760, Korea.ORCID 0000-0002-1517-7680
Ewha Womans University · KRKorea University · KR

Funding

Ministry of Food and Drug Safety 21162MFDS015-2Ministry of Science and ICT 2018R1A5A2025286
6 · The paper itself

Abstract

Cleaners such as dishwashing liquids contain various chemicals that cause skin damage. Alkaline agents used in cleaners alter the lipid composition of the skin and damage the skin barrier. However, little is known about the effects of acids used in cleaners on the skin. Here, we investigated the effects of acidic pH on the skin and evaluated the skin irritation of acids commonly used in cleaners with a 3D-reconstructed human epidermis model, KeraSkin

Indexed as

acidsalkaliscleanerpHreconstructed human epidermis modelskin irritation

Identifiers

PMID36287839
PMCPMC9610857
OpenAlexW4298003594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.