Evidence map›Paper›PMID 36287809›Full record

ArticleTomography (Ann Arbor, Mich.)2022

Clinical Value of Diffusion-Weighted Whole-Body Imaging with Background Body Signal Suppression (DWIBS) for Staging of Patients with Suspected Head and Neck Cancer.

Andreas Schicho, Werner Habicher, Christina Wendl, Christian Stroszczynski, Quirin Strotzer, Marco Dollinger, Andreas G Schreyer, Stephan Schleder

Open access · goldAbstract read
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Andreas SchichoDepartment of Radiology, University Medical Center Regensburg, 93053 Regensburg, Germany.ORCID 0000-0002-3648-0996
Werner HabicherDepartment of Othorhinolaryngology, Merciful Brothers Hospital St. Elisabeth, 94315 Straubing, Germany.
Christina WendlDepartment of Radiology, University Medical Center Regensburg, 93053 Regensburg, Germany.
Christian StroszczynskiDepartment of Radiology, University Medical Center Regensburg, 93053 Regensburg, Germany.
Quirin StrotzerDepartment of Radiology, University Medical Center Regensburg, 93053 Regensburg, Germany.ORCID 0000-0001-9093-2589
Marco DollingerDepartment of Radiology, University Medical Center Regensburg, 93053 Regensburg, Germany.
Andreas G SchreyerDepartment of Diagnostic and Interventional Radiology, University Hospital Brandenburg, Brandenburg Medical School Theodor Fontane, 14770 Neuruppin, Germany.
Stephan SchlederDepartment of Diagnostic and Interventional Radiology, Merciful Brothers Hospital St. Elisabeth, 94315 Straubing, Germany.ORCID 0000-0002-7785-3015
University Hospital Regensburg · DEMedizinische Hochschule Brandenburg Theodor Fontane · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: To determine the importance of diffusion-weighted whole-body MRI with background body signal suppression (DWIBS) in the staging process of patients with suspected head and neck carcinomas. (2) Methods: A total of 30 patients (24 male, 6 female) with a median age of 67 years with clinically suspected head and neck carcinoma with pathologic cervical nodal swelling in ultrasound underwent the staging procedure with computed tomography (CT) and whole-body MRI including DWIBS. (3) Results: In a total of 9 patients, abnormalities in the routine work-up of pretherapeutic staging were found. Five cases of either secondary cancer or distant metastases were only visible in DWIBS, while being missed on CT. One diagnosis was only detectable in CT and not in DWIBS, whereas three diagnoses were recognizable in both modalities. (4) Conclusions: DWIBS in addition to a standard neck MRI in cervical lymphadenopathy suspicious for head and neck cancer yielded additional clinically relevant diagnoses in 17% of cases that would have been missed by current staging routine procedures. DWIBS offered a negative predictive value of 98.78% for ruling out distant metastases or secondary malignancies.

Indexed as

Head and Neck NeoplasmsWhole Body ImagingAgedFemaleFluorodeoxyglucose F18HumansMaleMultimodal ImagingSensitivity and SpecificityFluorodeoxyglucose F18CTDWIBShead and neck carcinomametastasesstaging

Identifiers

PMID36287809
PMCPMC9607011
OpenAlexW4304187810

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.