SynthesisRevista latino-americana de enfermagem2022
Frailty and delirium in hospitalized older adults: A systematic review with meta-analysis.
Synthesis in Revista latino-americana de enfermagem, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Impact of frailty on postoperative delirium in ICU patients aged 65 and older: a systematic review.BMJ open · 2026Pooled it
- Mapping Research Trends in Frailty and Nutrition: A Combined Bibliometric and Structured Review (2000-2024).Nutrients · 2025Pooled it
- Bridging the gap in delirium management: a European comparison of geriatric practices.European geriatric medicine · 2026Article
- Association of Frailty and Delirium with Hospitalization Outcomes Among Older Adults With Rheumatic Diseases.ACR open rheumatology · 2026Article
- Dynamic frailty assessment predicts in-hospital and early post-discharge mortality in older patients hospitalized with acute heart failure: a prospective cohort study.BMC geriatrics · 2026Article
- Efficiency of Sorting Site of Care for Frail Patients Undergoing Mastectomy.Annals of surgical oncology · 2026Article
- Prevalence and interconnectedness of delirium, dementia, and frailty pathways in clinical settings: a survey of geriatricians across Europe.European geriatric medicine · 2026Article
- Frailty assessment in perioperative geriatric patients: a narrative review.Anesthesia and pain medicine · 2026Review
- Cognitive Decline in Hospitalized Older Adults: A Scoping Review.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2025Article
- The perceptions of European geriatricians on the co-occurrence and links between dementia, delirium and frailty.European geriatric medicine · 2025Article
- Depressive symptoms and frailty, effects of social distancing and isolation in older adults.Investigacion y educacion en enfermeria · 2025Article
- Risk of sarcopenia, frailty and malnutrition as predictors of postoperative delirium in surgery.BMC geriatrics · 2024Article
- Risk of falls is associated with 30-day mortality among older adults in the emergency department.The American journal of emergency medicine · 2024Observational
- Frailty in an Adult Acute Hospital Population: Predictors, Prevalence, and Outcomes.International journal of environmental research and public health · 2024Article
- Spanish transcultural adaptation of the 4AT score for the evaluation of delirium in the emergency department: a prospective diagnostic test accuracy study.BMC nursing · 2024Article
- To Be Frail or Not to Be Frail: This Is the Question-A Critical Narrative Review of Frailty.Journal of clinical medicine · 2024Review
- Clinical Significance of the Prognostic Nutritional Index in Predicting Delirium among Critically Ill Patients: A Retrospective Cohort Study.Critical care research and practice · 2024Article
- Hospital admission and the occurrence of delirium in older adults with physical frailty: cross-sectional study.Revista da Escola de Enfermagem da U S P · 2023Article
- Frailty Syndrome and sarcopenia in older adults with and without type 2 diabetes mellitus in the municipality of Sinop, Mato Grosso: an epidemiological study.Revista latino-americana de enfermagem · 2023Article
- Nursing microtheory in the prevention of delirium in older adult in the intensive care unit.Revista latino-americana de enfermagem · 2023Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveto estimate the prevalence and synthesize diverse evidence about the relationship between frailty and delirium in hospitalized older adults.
methoda systematic review with meta-analysis in which observational studies conducted with older adults about frailty, delirium and hospitalization, were selected without time of language restrictions. The search was conducted in the MEDLINE, EMBASE, CINAHL, Scopus, Web of Science and CENTRAL databases during August 2021. The precepts set forth by the Joanna Briggs Institute (JBI) - Evidence Synthesis Groups were followed. The meta-analysis model estimated the relative risk corresponding to the prevalence of frailty and delirium. The inverse variance method for proportions was used to estimate the prevalence values and relative risks for binary outcomes.
resultsinitially, 1,244 articles were identified, of which 26 were included in the meta-analysis (n=13,502 participants), with 34% prevalence of frailty (95% CI:0.26-0.42; I 2=99%; t 2=0.7618, p=0) and 21% for delirium (95% CI:0.17-0,25; I 2=95%; t 2=0.3454, p<0.01). The risk for hospitalized older adults to develop delirium was 66% (RR: 1.66; 95% CI:1.23-2.22; I2=92%; t2=0.4154; p<0.01).
conclusion34% prevalence of frailty and 21% of delirium in hospitalized older adults, with frailty being an independent risk factor for developing delirium, with an increased chance of 66% when compared to non-frail individuals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.