Evidence map›Paper›PMID 36287310›Full record

SynthesisClinical and experimental medicine2023

Systemic immune-inflammation index and the survival of hepatocellular carcinoma patients after transarterial chemoembolization: a meta-analysis.

Duqiang Li, Xiaoyan Zhao, Xingtao Pi, Kai Wang, Dong Song

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Clinical and experimental medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Prognostic significance of systemic immune-inflammation index in hepatocellular carcinoma: a meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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  15. Relationships Among Serological Indicators andCombinatorial chemistry & high throughput screening · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Duqiang Li *Department of Interventional Therapy, Shanxi Bethune Hospital, 99 Longcheng Street, Xiaodian District, Taiyuan, 030032, China. liduqiang_2020@163.com.
Xiaoyan Zhao *Department of Breast Surgery, Shanxi Maternal and Child Health Hospital, Taiyuan, 030013, China.
Xingtao PiDepartment of Interventional Therapy, Shanxi Bethune Hospital, 99 Longcheng Street, Xiaodian District, Taiyuan, 030032, China.
Kai WangDepartment of Image, Shanxi Bethune Hospital, Taiyuan, 030032, China.
Dong SongDepartment of Digestive System Oncology, Shanxi Bethune Hospital, Taiyuan, 030032, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The systemic immune-inflammation index (SII), derived from neutrophil, platelet, and lymphocyte counts, has been associated with prognosis of patients with cancer. We performed a meta-analysis to evaluate the association between pretreatment SII and survival of patients with hepatocellular carcinoma (HCC) after transarterial chemoembolization (TACE). Cohort studies were identified by search of PubMed, Embase, Web of Science, CNKI, and Wanfang databases. Pooling the results was achieved with a random-effect model that incorporates potential heterogeneity between studies. Nine studies including 3557 patients with HCC contributed to the meta-analysis. Compared to patients with a lower SII, HCC patients with a higher pretreatment SII had poor overall survival (OS, hazard ratio [HR] 1.66, 95% confidence interval [CI] 1.25-2.21, p < 0.001; I

Indexed as

Carcinoma, HepatocellularChemoembolization, TherapeuticLiver NeoplasmsHumansInflammationPrognosisRetrospective StudiesHepatocellular carcinomaMeta-analysisSurvivalSystemic immune-inflammation indexTransarterial chemoembolization

Identifiers

PMID36287310

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.