Evidence map›Paper›PMID 36286591›Full record

ArticleDiabetes care2022

Diabetes-Related Excess Mortality in Mexico: A Comparative Analysis of National Death Registries Between 2017-2019 and 2020.

Omar Yaxmehen Bello-Chavolla, Neftali Eduardo Antonio-Villa, Carlos A Fermín-Martínez, Luisa Fernández-Chirino, Arsenio Vargas-Vázquez, Daniel Ramírez-García, Martín Roberto Basile-Alvarez, Ana Elena Hoyos-Lázaro, Rodrigo M Carrillo-Larco, Deborah J Wexler and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Mortality from type 2 diabetes mellitus across municipalities in Mexico.Archives of public health = Archives belges de sante publique · 2024
    Article
  13. Article
  14. Review
  15. Article
  16. The Legacy of President Lázaro Cárdenas for Health Care Reform in Today's Mexico.International journal of social determinants of health and health services · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 4 countries.

Omar Yaxmehen Bello-ChavollaResearch Division, Instituto Nacional de Geriatría, Mexico City, Mexico.ORCID 0000-0003-3093-937X
Neftali Eduardo Antonio-VillaResearch Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
Carlos A Fermín-MartínezResearch Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
Luisa Fernández-ChirinoResearch Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
Arsenio Vargas-VázquezMD/PhD (PECEM) Program, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Daniel Ramírez-GarcíaResearch Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
Martín Roberto Basile-AlvarezResearch Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
Ana Elena Hoyos-LázaroResearch Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
Rodrigo M Carrillo-LarcoDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, U.K.
Deborah J WexlerDiabetes Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Jennifer Manne-GoehlerHarvard Center for Population and Development Studies, Harvard T.H. Chan School of Public Health, Boston, MA.
Jacqueline A SeiglieDiabetes Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Instituto Nacional de Pediatria · MXHarvard University · USUniversidad Nacional Autónoma de México · MXUniversidad Peruana Cayetano Heredia · PE

Funding

Institutional Career Development CoreKL2TR002542 · NCATS · HARVARD MEDICAL SCHOOL · PI BREDELLA, MIRIAM ANTOINETTE, RUTKOVE, SEWARD B. · 2018 to 2022
$8.7M
Preventing Weight Gain and Diabetes in People with HIV in South AfricaK23DK125162 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI MANNE-GOEHLER, JENNIFER · 2020 to 2024
$986k
NCATS NIH HHS KL2 TR002542NIDDK NIH HHS K23 DK125162Wellcome Trust 214185Wellcome Trust 214185/Z/18/Z
6 · The paper itself

Abstract

objectiveTo estimate diabetes-related mortality in Mexico in 2020 compared with 2017-2019 after the onset of the coronavirus disease 2019 (COVID-19) pandemic. RESEARCH DESIGN AND

methodsThis retrospective, state-level study used national death registries of Mexican adults aged ≥20 years for the 2017-2020 period. Diabetes-related death was defined using ICD-10 codes listing diabetes as the primary cause of death, excluding certificates with COVID-19 as the primary cause of death. Spatial and negative binomial regression models were used to characterize the geographic distribution and sociodemographic and epidemiologic correlates of diabetes-related excess mortality, estimated as increases in diabetes-related mortality in 2020 compared with average 2017-2019 rates.

resultsWe identified 148,437 diabetes-related deaths in 2020 (177 per 100,000 inhabitants) vs. an average of 101,496 deaths in 2017-2019 (125 per 100,000 inhabitants). In-hospital diabetes-related deaths decreased by 17.8% in 2020 versus 2017-2019, whereas out-of-hospital deaths increased by 89.4%. Most deaths were attributable to type 2 diabetes (130 per 100,000 inhabitants). Compared with 2018-2019 data, hyperglycemic hyperosmolar state and diabetic ketoacidosis were the two contributing causes with the highest increase in mortality (128% and 116% increase, respectively). Diabetes-related excess mortality clustered in southern Mexico and was highest in states with higher social lag, rates of COVID-19 hospitalization, and prevalence of HbA1c ≥7.5%.

conclusionsDiabetes-related deaths increased among Mexican adults by 41.6% in 2020 after the onset of the COVID-19 pandemic, occurred disproportionately outside the hospital, and were largely attributable to type 2 diabetes and hyperglycemic emergencies. Disruptions in diabetes care and strained hospital capacity may have contributed to diabetes-related excess mortality in Mexico during 2020.

Indexed as

COVID-19Diabetes Mellitus, Type 2AdultCause of DeathHumansMexicoMortalityPandemicsRegistriesRetrospective Studies

Identifiers

PMID36286591
PMCPMC7613876
OpenAlexW4307492670

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.