Evidence map›Paper›PMID 36286588›Full record

ArticleHealth security

The Promise of Emergent Nanobiotechnologies for In Vivo Applications and Implications for Safety and Security.

Anne M Arnold, Ashley M Bradley, Karen L Taylor, Zachary C Kennedy, Kristin M Omberg

Abstract read
In one paragraph

Article in Health security. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Silver Compounds for Caries Management.International dental journal · 2024
    Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anne M ArnoldAnne M. Arnold, PhD, is a Materials Scientist, National Security Directorate, Pacific Northwest National Laboratory, Richland, WA.
Ashley M BradleyAshley M. Bradley is a Biomedical Scientist, National Security Directorate, Pacific Northwest National Laboratory, Richland, WA.
Karen L TaylorKaren L. Taylor, MPH, is a Senior Technical Advisor, National Security Directorate, Pacific Northwest National Laboratory, Seattle, WA.
Zachary C KennedyZachary C. Kennedy, PhD, is a Materials Scientist, National Security Directorate, Pacific Northwest National Laboratory, Richland, WA.
Kristin M OmbergKristin M. Omberg, PhD, is Group Leader, National Security Directorate, Pacific Northwest National Laboratory, Richland, WA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanotechnology, the multidisciplinary field based on the exploitation of the unique physicochemical properties of nanoparticles (NPs) and nanoscale materials, has opened a new realm of possibilities for biological research and biomedical applications. The development and deployment of mRNA-NP vaccines for COVID-19, for example, may revolutionize vaccines and therapeutics. However, regulatory and ethical frameworks that protect the health and safety of the global community and environment are lagging, particularly for nanotechnology geared toward biological applications (ie, bionanotechnology). In this article, while not comprehensive, we attempt to illustrate the breadth and promise of bionanotechnology developments, and how they may present future safety and security challenges. Specifically, we address current advancements to streamline the development of engineered NPs for in vivo applications and provide discussion on nano-bio interactions, NP in vivo delivery, nanoenhancement of human performance, nanomedicine, and the impacts of NPs on human health and the environment.

Indexed as

COVID-19COVID-19 VaccinesHumansNanomedicineNanotechnologyRNA, MessengerCOVID-19 VaccinesRNA, MessengerBiosafety protectionBiotech industryCode of conductDual-use scienceNanoparticles

Identifiers

PMID36286588
PMCPMC9595614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.