Evidence map›Paper›PMID 36286547›Full record

ArticleEmerging infectious diseases2022

Increased Detection of Carbapenemase-Producing Enterobacterales Bacteria in Latin America and the Caribbean during the COVID-19 Pandemic.

Genara Romero Thomas, Alejandra Corso, Fernando Pasterán, Justina Shal, Aldo Sosa, Marcelo Pillonetto, Renata Tigulini de Souza Peral, Juan Carlos Hormazábal, Pamela Araya, Sandra Yamile Saavedra and 21 more

Registry-linked trialAbstract read
In one paragraph

Article in Emerging infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07167173 (Predictive Model for Multidrug Resistance in Patients Admitted to the Emergency Department With Sepsis), which is not on this map. Cited by 65 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07167173 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Predictive Model for Multidrug Resistance in Patients Admitted to the Emergency Department With Sepsis

TypeobservationalSponsorHospital Italiano de Buenos AiresRan2025 to 2025Enrolled10,000ConditionsSepsis, Septic Shock
3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Microbiology spectrum · 2026
    Article
  5. Article
  6. Review
  7. Incidence of colonization and infection with carbapenemase-producing Enterobacterales in Toronto and Peel Region, Ontario, 2007-2024.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2026
    Article
  8. Article
  9. Expanding Threat of Carbapenemase-ProducingbioRxiv : the preprint server for biology · 2026
    Article
  10. Article
  11. Epidemiological Insights into Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2026
    Article
  12. Review
  13. JAC-antimicrobial resistance · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. First nationwide survey onAntimicrobial agents and chemotherapy · 2025
    Article
  18. Article
  19. Article
  20. Molecular characterization of blaBMC infectious diseases · 2025
    Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Genara Romero Thomas
Alejandra Corso
Fernando Pasterán
Justina Shal
Aldo Sosa
Marcelo Pillonetto
Renata Tigulini de Souza Peral
Juan Carlos Hormazábal
Pamela Araya
Sandra Yamile Saavedra
Mariá Victoria Ovalle
María Antonieta Jiménez Pearson
Grettel Chanto Chacón
Eric Carbon
Carmen Julia Mazariegos Herrera
Selene Del Carmen González Velásquez
Carolina Satan-Salazar
Fernando Villavicencio
Nancy Melgarejo Touchet
Sofía Busignani
Maritza Mayta-Barrios
Juan Ramírez-Illescas
Mariana López Vega
Cristina Mogdasy
Verónica Rosas
Nuris Salgado
Rodolfo Quiroz
Nathalie El-Omeiri
Marcelo Fabián Galas
Pilar Ramón-Pardo
Roberto Gustavo Melano

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During 2020-2021, countries in Latin America and the Caribbean reported clinical emergence of carbapenemase-producing Enterobacterales that had not been previously characterized locally, increased prevalence of carbapenemases that had previously been detected, and co-production of multiple carbapenemases in some isolates. These increases were likely fueled by changes related to the COVID-19 pandemic, including empirical antibiotic use for potential COVID-19-related bacterial infections and healthcare limitations resulting from the rapid rise in COVID-19 cases. Strengthening antimicrobial resistance surveillance, epidemiologic research, and infection prevention and control programs and antimicrobial stewardship in clinical settings can help prevent emergence and transmission of carbapenemase-producing Enterobacterales.

Indexed as

COVID-19Anti-Bacterial AgentsBacteriaBacterial Proteinsbeta-LactamasesHumansLatin AmericaPandemicsAnti-Bacterial AgentsBacterial Proteinsbeta-Lactamasescarbapenemaseantimicrobial resistancebacteriacarbapenemase-producing Enterobacteralescoronaviruscoronavirus diseaseCorso ACOVID-19enteric infectionset al. Increased detection of carbapenemase-producing Enterobacterales bacteria in Latin America and the Caribbean during the COVID-19 pandemic. Emerg Infect Dis. 2022 Nov [date cited]. https://doi.org/10.3201/eid2811.220415food safetyLatin AmericaPasterán FPillonetto Mrespiratory infectionsSARSSARS-CoV-2severe acute respiratory syndrome coronavirus 2Shal JSosa ASuggested citation for this article: Romero Thomas Gthe Caribbeanviruseszoonoses

Identifiers

PMID36286547
PMCPMC9622262

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.