Evidence map›Paper›PMID 36286526›Full record

ArticleInfection and immunity2022

Differential Response to the Course of Cryptosporidium parvum Infection and Its Impact on Epithelial Integrity in Differentiated versus Undifferentiated Human Intestinal Enteroids.

Hymlaire Lamisere, Seema Bhalchandra, Anne V Kane, Xi-Lei Zeng, Devons Mo, Walter Adams, Mary K Estes, Honorine D Ward

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  3. Virulence · 2025
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  8. Microphysiological gut-on-chip enables extendedFrontiers in cellular and infection microbiology · 2025
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  9. Review
  10. Rapid review: Recent advances inCurrent research in parasitology & vector-borne diseases · 2025
    Review
  11. Apical-out bovine intestinal organoids as an infection model forCurrent research in parasitology & vector-borne diseases · 2025
    Article
  12. Article
  13. Review
  14. Frontiers in cellular and infection microbiology · 2024
    Article
  15. Murine colon organoids as a novel model to studyFrontiers in cellular and infection microbiology · 2023
    Article
  16. Gut microbes
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Hymlaire Lamisere *Tufts University Graduate School of Biomedical Sciences, Boston, Massachusetts, USA.
Seema Bhalchandra *Tufts Medical Centergrid.67033.31, Boston, Massachusetts, USA.
Anne V KaneTufts Medical Centergrid.67033.31, Boston, Massachusetts, USA.
Xi-Lei ZengDepartment of Molecular Virology, Baylor College of Medicinegrid.39382.33, Houston, Texas, USA.
Devons MoDepartment of Biological Sciences, San Jose State University, San Jose, California, USA.
Walter AdamsDepartment of Biological Sciences, San Jose State University, San Jose, California, USA.ORCID 0000-0002-2979-1382
Mary K EstesDepartment of Molecular Virology, Baylor College of Medicinegrid.39382.33, Houston, Texas, USA.ORCID 0000-0002-4813-4249
Honorine D WardTufts University Graduate School of Biomedical Sciences, Boston, Massachusetts, USA.
Baylor College of Medicine · USSan Jose State University · USTufts Medical Center · USTufts University · US

Funding

Interaction of enteropathogenic Yersinia and Vibrio cholera with engineered human intestinal tissueU19AI131126 · NIAID · TUFTS UNIVERSITY BOSTON · PI ISBERG, RALPH R., KAPLAN, DAVID L. · 2017 to 2021
$8.1M
IMMUNOLOGIC ASPECTS OF DISEASET32AI007077 · NIAID · TUFTS UNIVERSITY BOSTON · PI WORTIS, HENRY H. · 1985 to 2017
$3.5M
Tufts-CMC Framework Program for Global Health InnovationD43TW009377 · FIC · TUFTS UNIVERSITY BOSTON · PI KANG, GAGANDEEP, WANKE, CHRISTINE A · 2013 to 2017
$1.6M
Microbial and Host Factors that Promote Epithelial Disruption and S. pneumoniae Transit out of the LungSC2GM141988 · NIGMS · SAN JOSE STATE UNIVERSITY · PI ADAMS, WALTER ISAIAH · 2021 to 2023
$440k
FIC NIH HHS D43 TW009377NIAID NIH HHS T32 AI007077NIAID NIH HHS U19 AI131126NIGMS NIH HHS SC2 GM141988
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CryptosporidiosisCryptosporidiumCryptosporidium parvumChildChild, PreschoolDiarrheaHumansIntestinal MucosaIntestinesCryptosporidiumenteroidintestinal epithelial integrity

Identifiers

PMID36286526
PMCPMC9671013
OpenAlexW4307340594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.