Evidence map›Paper›PMID 36286465›Full record

ReviewMarine drugs2022

The Tetrahydrofuran Motif in Marine Lipids and Terpenes.

Paula González-Andrés, Laura Fernández-Peña, Carlos Díez-Poza, Asunción Barbero

Abstract readReview
In one paragraph

Review in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. 2-Butoxytetrahydrofuran, Isolated fromACS chemical neuroscience · 2024
    Article
  5. Ligand-Enabled Double γ-C(spAngewandte Chemie (International ed. in English) · 2023
    Article
  6. Coral Lipids.Marine drugs · 2023
    Review
  7. Lipids and Terpenoids from the Deep-Sea FungusMolecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paula González-AndrésDepartment of Organic Chemistry, Campus Miguel Delibes, University of Valladolid, 47011 Valladolid, Spain.
Laura Fernández-PeñaDepartment of Organic Chemistry, Campus Miguel Delibes, University of Valladolid, 47011 Valladolid, Spain.
Carlos Díez-PozaDepartamento de Química Orgánica y Química Inorgánica, Facultad de Farmacia e Instituto de Investigación Química Andrés M. del Río (IQAR), Universidad de Alcalá, Ctra. Madrid-Barcelona, 28871 Madrid, Spain.ORCID 0000-0002-9613-0680
Asunción BarberoDepartment of Organic Chemistry, Campus Miguel Delibes, University of Valladolid, 47011 Valladolid, Spain.ORCID 0000-0001-6825-7775

Funding

Junta de Castilla y León VA294-P18
6 · The paper itself

Abstract

Heterocycles are particularly common moieties within marine natural products. Specifically, tetrahydrofuranyl rings are present in a variety of compounds which present complex structures and interesting biological activities. Focusing on terpenoids, a high number of tetrahydrofuran-containing metabolites have been isolated during the last decades. They show promising biological activities, making them potential leads for novel antibiotics, antikinetoplastid drugs, amoebicidal substances, or anticancer drugs. Thus, they have attracted the attention of the synthetics community and numerous approaches to their total syntheses have appeared. Here, we offer the reader an overview of marine-derived terpenoids and related compounds, their isolation, structure determination, and a special focus on their total syntheses and biological profiles.

Indexed as

Antineoplastic AgentsBiological ProductsAnti-Bacterial AgentsFuransLipidsTerpenesAnti-Bacterial AgentsAntineoplastic AgentsBiological ProductsFuransLipidsTerpenesbiological activityfatty acidsmarine natural productsoxygen heterocyclesterpenestetrahydrofurantotal synthesis

Identifiers

PMID36286465
PMCPMC9605582

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.