Evidence map›Paper›PMID 36286434›Full record

ArticleMarine drugs2022

In Silico Analysis of Bioactive Peptides Produced from Underutilized Sea Cucumber By-Products-A Bioinformatics Approach.

Tharindu R L Senadheera, Abul Hossain, Deepika Dave, Fereidoon Shahidi

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Bioactive Peptides From theFood science & nutrition · 2026
    Review
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  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. The Effect ofFoods (Basel, Switzerland) · 2025
    Article
  11. The Identification and Synthesis of New Sea Cucumber Peptides Leveraging Peptidomics Technology, along with their Anti-Parkinson's Disease Efficacy.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. MicroalgaFoods (Basel, Switzerland) · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tharindu R L SenadheeraDepartment of Biochemistry, Memorial University of Newfoundland, St. John's, NL A1C 5S7, Canada.ORCID 0000-0002-3709-3541
Abul HossainDepartment of Biochemistry, Memorial University of Newfoundland, St. John's, NL A1C 5S7, Canada.ORCID 0000-0002-7519-8555
Deepika DaveDepartment of Biochemistry, Memorial University of Newfoundland, St. John's, NL A1C 5S7, Canada.ORCID 0000-0003-4358-3181
Fereidoon ShahidiDepartment of Biochemistry, Memorial University of Newfoundland, St. John's, NL A1C 5S7, Canada.ORCID 0000-0002-9912-0330
Memorial University of Newfoundland · CA

Funding

Natural Sciences and Engineering Research Council RGPIN-2015-06121Natural Sciences and Engineering Research Council RGPIN-2016-04468
6 · The paper itself

Abstract

Bioinformatic tools are widely used in predicting potent bioactive peptides from food derived materials. This study was focused on utilizing sea cucumber processing by-products for generating antioxidant and ACE inhibitory peptides by application of a range of in silico techniques. Identified peptides using LC-MS/MS were virtually screened by PepRank technique followed by in silico proteolysis simulation with representative digestive enzymes using BIOPEP-UWM

Indexed as

Computational BiologySea CucumbersAngiotensin-Converting Enzyme InhibitorsAnimalsAntioxidantsChromatography, LiquidPeptidesPharmaceutical PreparationsTandem Mass SpectrometryAngiotensin-Converting Enzyme InhibitorsAntioxidantsPeptidesPharmaceutical Preparationsbioactive peptidesbioinformaticssea cucumber by-productsvalue addition

Identifiers

PMID36286434
PMCPMC9605078
OpenAlexW4297477901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.