Evidence map›Paper›PMID 36286419›Full record

ArticleMarine drugs2022

Cytotoxic Potential of the Marine Diatom

Adele Cutignano, Mariarosaria Conte, Virginia Tirino, Vitale Del Vecchio, Roberto De Angelis, Angela Nebbioso, Lucia Altucci, Giovanna Romano

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Marine life science & technology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Adele CutignanoInstitute of Biomolecular Chemistry, National Research Council, Via Campi Flegrei 34, 80078 Pozzuoli, Italy.ORCID 0000-0003-3035-9252
Mariarosaria ConteDepartment of Precision Medicine, University of Campania 'L. Vanvitelli', Via L. De Crecchio 7, 80138 Napoli, Italy.ORCID 0000-0002-3622-1476
Virginia TirinoDepartment of Experimental Medicine, Section of Biotechnology, Molecular Medicine and Medical Histology, University of Campania "L. Vanvitelli", Via L. de Crecchio 7, 80138 Napoli, Italy.
Vitale Del VecchioDepartment of Experimental Medicine, Section of Biotechnology, Molecular Medicine and Medical Histology, University of Campania "L. Vanvitelli", Via L. de Crecchio 7, 80138 Napoli, Italy.ORCID 0000-0002-7323-4444
Roberto De AngelisDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via Akton 55, 80133 Napoli, Italy.
Angela NebbiosoDepartment of Precision Medicine, University of Campania 'L. Vanvitelli', Via L. De Crecchio 7, 80138 Napoli, Italy.ORCID 0000-0001-5374-3527
Lucia AltucciDepartment of Precision Medicine, University of Campania 'L. Vanvitelli', Via L. De Crecchio 7, 80138 Napoli, Italy.ORCID 0000-0002-7312-5387
Giovanna RomanoDepartment of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via Akton 55, 80133 Napoli, Italy.ORCID 0000-0002-4898-7153
University of Campania "Luigi Vanvitelli" · ITStazione Zoologica Anton Dohrn · IT

Funding

Campania Regional Government B63D18000560007Campania Regional Government Technology Platform B21C17000030007Ministero dell'Ambiente e della Tutela del Territorio e del Mare Grant ID: PGR00765
6 · The paper itself

Abstract

Marine microalgae are receiving great interest as sustainable sources of bioactive metabolites for health, nutrition and personal care. In the present study, a bioassay-guided screening allowed identifying an enriched fraction from SPE separation of the methanolic extract of the marine diatom

Indexed as

DiatomsPhytosterolsCaspase 3Caspase 9CholesterolPhytolSterolsCaspase 3Caspase 9CholesterolPhytolPhytosterolsSterols24-methylene cholesterolcancercell cycle arrestcytotoxicitydiatomsphytosterolsproapoptotic compoundsThalassiosira rotula

Identifiers

PMID36286419
PMCPMC9604713
OpenAlexW4297236471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.