ReviewJournal of cardiovascular development and disease2022
Inadvertent Lead Malposition in the Left Heart during Implantation of Cardiac Electric Devices: A Systematic Review.
Review in Journal of cardiovascular development and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Delayed Septal Perforation Presenting as Ischaemic Stroke: A Rare Complication of Left Bundle Branch Pacing.JACC. Case reports · 2026Article
- Percutaneous removal of an inadvertent left-heart implantable cardioverter-defibrillator lead malposition in a nonagenarian: A case report.HeartRhythm case reports · 2026Article
- Phrenic Nerve Stimulation-Induced Persistent Singultus: A Case of Atrial Lead Dislodgement After Dual-Chamber Pacemaker Implant.Journal of Brown hospital medicine · 2026Article
- Inadvertent left ventricular lead placement causing left bundle branch block paced electrocardiogram: A unique case.HeartRhythm case reports · 2025Article
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- A right wire in the wrong place.Internal and emergency medicine · 2024Article
- Novel Device Therapies for Heart Failure.Journal of cardiovascular development and disease · 2023Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe inadvertent lead malposition in the left heart (ILMLH) is an under-recognized event, which may complicate the implantation of cardiac electronic devices (CIEDs).
methodsWe investigated the clinical conditions associated with ILMLH and the treatment strategies in these patients. We made a systematic review of the literature and identified 132 studies which reported 157 patients with ILMLH.
resultsThe mean age of patients was 68 years, and 83 were women. ILMLH was diagnosed, on average, 365 days after CIEDs implantation. Coexisting conditions were patent foramen ovale in 29% of patients, arterial puncture in 24%, perforation of the interatrial septum in 20%, atrial septal defect in 16% and perforation of the interventricular septum in 4%. At the time of diagnosis of ILMLH, 46% of patients were asymptomatic, 31% had acute TIA or stroke and 15% had overt heart failure. Overall, 14% of patients were receiving anticoagulants at the time of diagnosis of ILMLH. After diagnosis of ILMLH, percutaneous or surgical lead extraction was carried out in 93 patients (59%), whereas 43 (27%) received anticoagulation. During a mean 9-month follow-up after diagnosis of ILMLH, four patients experienced TIA or stroke (three on oral anticoagulant therapy and one after percutaneous lead extraction).
conclusionILMLH is a rare complication, which is usually diagnosed about one year after implantation of CIEDs. An early diagnosis of ILMLH is important. Lead extraction is a safe and effective alternative to anticoagulants.
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