Evidence map›Paper›PMID 36286233›Full record

ArticleACS nano2022

Aptamer-Modified Au Nanoparticles: Functional Nanozyme Bioreactors for Cascaded Catalysis and Catalysts for Chemodynamic Treatment of Cancer Cells.

Yu Ouyang, Michael Fadeev, Pu Zhang, Raanan Carmieli, Jiang Li, Yang Sung Sohn, Ola Karmi, Rachel Nechushtai, Eli Pikarsky, Chunhai Fan and 1 more

Open access · hybridAbstract read
In one paragraph

Article in ACS nano, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 103 citations in OpenAlex.

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  12. Nucleic Acid-Modified Nanoparticles for Cancer Therapeutic Applications.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
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  20. DNA Catalysis: Design, Function, and Optimization.Molecules (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Yu OuyangThe Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.ORCID 0000-0002-2418-281X
Michael FadeevThe Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Pu ZhangThe Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Raanan CarmieliDepartment of Chemical Research Support, Weizmann Institute of Science, Rehovot 76100, Israel.ORCID 0000-0003-4418-916X
Jiang LiSchool of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.ORCID 0000-0003-2372-6624
Yang Sung SohnInstitute of Life Science, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Ola KarmiInstitute of Life Science, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Rachel NechushtaiInstitute of Life Science, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.ORCID 0000-0002-3219-954X
Eli PikarskyThe Lautenberg Center for Immunology and Cancer Research, IMRIC, The Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Chunhai FanSchool of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.ORCID 0000-0002-7171-7338
Itamar WillnerThe Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.ORCID 0000-0001-9710-9077
Hebrew University of Jerusalem · ILShanghai Jiao Tong University · CNWeizmann Institute of Science · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyadenine-stabilized Au nanoparticles (pA-AuNPs) reveal dual nanozyme catalytic activities toward the H

Indexed as

Metal NanoparticlesNeoplasmsBioreactorsCatalysisDopamineGlucoseGoldHydrogen PeroxideIndolequinonesaminochrome 1DopamineGlucoseGoldHydrogen PeroxideIndolequinonesChemodynamic cancer therapyDNA nanotechnologyNanozymeOxidasePeroxidaseReactive oxygen species (ROS)

Identifiers

PMID36286233
PMCPMC9706657
OpenAlexW4307340647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.