ArticleGels (Basel, Switzerland)2022
One-Step Preparation of Carboxymethyl Cellulose-Phytic Acid Hydrogels with Potential for Biomedical Applications.
Article in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Phosphorus-Doped Cellulose-Derived Carbon Aerogel for Synergistic Adsorption of Congo Red and Cu(II) from Complex Wastewater.ACS omega · 2026Article
- Biopolymer-Based Hydrogels for Wound Healing: Advances in Cellulose, Chitosan, Alginate, and Hyaluronic Acid from Design to Clinical Translation.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Development and in vitro evaluation of a xylitol/erythritol carbomer gel for xerostomia relief.Odontology · 2026Article
- Article
- Hydrogels from Renewable Resources: Advances in 3D Networks Based on Cellulose and Hemicellulose.Polymers · 2025Review
- A Scoping Review of Recent Developments in Cellulose-Derived Hydrogels for Dental Applications.Pharmaceutics · 2025Review
- Stimulus-responsive cellulose hydrogels in biomedical applications and challenges.Materials today. Bio · 2025Review
- Structural and Gelation Characteristics of Alkali-Soluble β-Glucan fromGels (Basel, Switzerland) · 2025Article
- Enhancing Cross-Linking Efficiency in Gelatin-Based Hydrogels via Incorporation of Tannic Acid, Pluronic F-127, and Phytic Acid.Polymers · 2025Article
- Development of Eco-Friendly Date Palm Biomass-Based Hydrogels for Enhanced Water Retention in Soil.Gels (Basel, Switzerland) · 2025Article
- Exploring Applications and Preparation Techniques for Cellulose Hydrogels: A Comprehensive Review.Gels (Basel, Switzerland) · 2024Review
- Development and Characterization of Gelatin-Based Hydrogels Containing Triblock Copolymer and Phytic Acid.Gels (Basel, Switzerland) · 2024Article
- Dual-Responsive Hydrogels for Mercury Ion Detection and Removal from Wastewater.Gels (Basel, Switzerland) · 2024Article
- Alginate-Based Hydrogels Enriched with Lavender Essential Oil: Evaluation of Physicochemical Properties, Antimicrobial Activity, and In Vivo Biocompatibility.Pharmaceutics · 2023Article
- A Review of Patents and Innovative Biopolymer-Based Hydrogels.Gels (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hydrogels based on natural, biodegradable materials have gained considerable interest in the medical field due to their improved drug delivery profiles and tissue-mimicking architecture. In this regard, this study was devoted to the preparation and characterization of new physically crosslinked hydrogels based on carboxymethyl cellulose and an unconventional crosslinking agent, phytic acid. Phytic acid, in addition to its antioxidant and antibacterial effects, can improve the biological properties and stability of gels, without adding toxicity. Fourier transform infrared (FTIR) spectroscopy, rheological studies and thermal analysis confirmed the hydrogel formation. The influence of the ratio between the cellulose derivative and the crosslinker upon the morphological structure and water uptake was evidenced by scanning electron microscopy (SEM) and swelling measurements in simulated body fluids. Furthermore, procaine was entrapped within the hydrogels and used as a model drug for in vitro studies, which highlighted the dependence of the drug release on the phytic acid content of the matrix. The materials demonstrated antibacterial effects against
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.