Evidence map›Paper›PMID 36286095›Full record

ArticleBiomaterials science2022

Cyclodextrin metal-organic framework-based protein biocomposites.

Giuseppe Di Palma, Shannon Geels, Brooke P Carpenter, Rain A Talosig, Charles Chen, Francesco Marangoni, Joseph P Patterson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomaterials science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giuseppe Di PalmaDepartment of Chemistry, University of California Irvine, Irvine, California 92697, USA. patters3@uci.edu.
Shannon GeelsDepartment of Physiology and Biophysics, University of California Irvine, Irvine, CA 92697, USA.
Brooke P CarpenterDepartment of Chemistry, University of California Irvine, Irvine, California 92697, USA. patters3@uci.edu.
Rain A TalosigDepartment of Chemistry, University of California Irvine, Irvine, California 92697, USA. patters3@uci.edu.
Charles ChenDepartment of Chemistry, University of California Irvine, Irvine, California 92697, USA. patters3@uci.edu.
Francesco MarangoniDepartment of Physiology and Biophysics, University of California Irvine, Irvine, CA 92697, USA.
Joseph P PattersonDepartment of Chemistry, University of California Irvine, Irvine, California 92697, USA. patters3@uci.edu.ORCID http://orcid.org/0000-0002-1975-1854

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
NCI NIH HHS P30 CA062203
6 · The paper itself

Abstract

Materials are needed to increase the stability and half-life of therapeutic proteins during delivery. These materials should be biocompatible and biodegradable. Here, we demonstrate that enzymes and immunoproteins can be encapsulated inside cyclodextrin based metal-organic frameworks using potassium as the metal node. The release profile can be controlled with the solubility of the cyclodextrin linker. The activity of the proteins after release is determined using catalytic and

Indexed as

CyclodextrinsMetal-Organic FrameworksMetalsProteinsSolubilityCyclodextrinsMetal-Organic FrameworksMetalsProteins

Identifiers

PMID36286095
PMCPMC9717710

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.