Evidence map›Paper›PMID 36285600›Full record

Observational studyInternational journal of STD & AIDS2023

Maternal retention and early infant HIV diagnosis in a prospective cohort study of HIV-positive women and their children in Malawi.

Marina Giuliano, Stefano Orlando, Mauro Andreotti, Bryan Mthiko, Robert Mphwere, Thom Kavalo, Fausto Ciccacci, Maria Cristina Marazzi, Marco Floridia

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in International journal of STD & AIDS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Marina GiulianoNational Center for Global Health, 9289Istituto Superiore di Sanità, Rome, Italy.ORCID 0000-0003-2789-7797
Stefano OrlandoDepartment of Biomedicine and Prevention, 9318University of Rome Tor Vergata, Rome, Italy.
Mauro AndreottiNational Center for Global Health, 9289Istituto Superiore di Sanità, Rome, Italy.
Bryan MthikoDREAM Program, Community of S. Egidio, Blantyre, Malawi.
Robert MphwereDREAM Program, Community of S. Egidio, Blantyre, Malawi.
Thom KavaloDREAM Program, Community of S. Egidio, Blantyre, Malawi.
Fausto CiccacciUniCamillus, 528488Saint Camillus International University of Health Sciences, Rome, Italy.
Maria Cristina MarazziDepartment of Human Sciences, 19011LUMSA University, Rome, Italy.
Marco FloridiaNational Center for Global Health, 9289Istituto Superiore di Sanità, Rome, Italy.ORCID 0000-0003-3971-0141
Blantyre Institute for Community Ophthalmology · MWIstituto Superiore di Sanità · ITLibera Università Maria SS. Assunta · ITSaint Camillus International University of Health and Medical Sciences · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPost-partum loss to follow-up and lack of early HIV infant diagnosis (EID) can significantly affect the efficiency of programs for the prevention of mother-to-child transmission.

methodsIn a prospective observational study 167 women were enrolled at week 36 of gestation and followed with their infants up to one year after delivery. Retention was defined as the proportion of women who attended the 12 months visit and EID as an HIV PCR test performed within 2 months. Determinants for retention and EID were assessed in univariate analyses and in multivariable logistic regression models.

resultsWomen lost to follow-up (24/167 or 14.4%) had a shorter duration of antiretroviral therapy (ART) at enrolment in comparison to women retained in care (

conclusionsLonger duration of ART at enrolment significantly predicted a better post-partum retention, suggesting that specific counselling interventions should be targeted to recent ART initiators. A low proportion of infants did not receive an EID, but predictive factors were difficult to identify.

Indexed as

HIV InfectionsPregnancy Complications, InfectiousEarly DiagnosisFemaleHumansInfantInfectious Disease Transmission, VerticalMalawiPregnancyProspective Studiesearly infant diagnosisHIVMalawipostpartumprevention of mother-to-child transmissionretention

Identifiers

PMID36285600
PMCPMC10658750
OpenAlexW4307256473

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.