ArticlePsychophysiology2023
Association between PTSD and Impedance Cardiogram-based contractility metrics during trauma recall: A controlled twin study.
Article in Psychophysiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 5 citations in OpenAlex.
- Ambulatory autonomic nervous system activity in relation to hearing impairment.Psychophysiology · 2025Article
- Exaggerated Peripheral and Systemic Vasoconstriction During Trauma Recall in Posttraumatic Stress Disorder: A Co-Twin Control Study.Biological psychiatry · 2024Article
- Impedance cardiogram based exploration of cardiac mechanisms in post-traumatic stress disorder during trauma recall.Psychophysiology · 2024Article
- Dog ownership may promote cardiometabolic health in U.S. military veterans.Scientific reports · 2023Article
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Authors and funding
15 authors at 3 institutions in 1 country.
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Abstract
Post-traumatic stress disorder (PTSD) is an independent risk factor for incident heart failure, but the underlying cardiac mechanisms remained elusive. Impedance cardiography (ICG), especially when measured during stress, can help understand the underlying psychophysiological pathways linking PTSD with heart failure. We investigated the association between PTSD and ICG-based contractility metrics (pre-ejection period (PEP) and Heather index (HI)) using a controlled twin study design with a laboratory-based traumatic reminder stressor. PTSD status was assessed using structured clinical interviews. We acquired synchronized electrocardiograms and ICG data while playing personalized-trauma scripts. Using linear mixed-effects models, we examined twins as individuals and within PTSD-discordant pairs. We studied 137 male veterans (48 pairs, 41 unpaired singles) from Vietnam War Era with a mean (standard deviation) age of 68.5(2.5) years. HI during trauma stress was lower in the PTSD vs. non-PTSD individuals (7.2 vs. 9.3 [ohm/s
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