Evidence map›Paper›PMID 36285386›Full record

ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

In-hospital Mortality Rates in SARS-CoV-2 Patients Treated with Enoxaparin and Heparin.

Moudhi Alroomi, Ahmad Alsaber, Bader Al-Bader, Farah Almutairi, Haya Malhas, Jiazhu Pan, Kobalava D Zhanna, Maryam Ramadhan, Mohammad Al Saleh, Mohammed Abdullah and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 3 countries.

Moudhi AlroomiDepartment of Infectious Diseases, Infectious Diseases Hospital, Shuwaikh Medical Area, Kuwait.ORCID 0000-0001-6907-011X
Ahmad AlsaberDepartment of Mathematics and Statistics, University of Strathclyde, Glasgow, UK.
Bader Al-BaderDepartment of Medicine, Farwaniya Hospital, Farwaniya, Kuwait.
Farah AlmutairiDepartment of Medicine, Farwaniya Hospital, Farwaniya, Kuwait.
Haya MalhasDepartment of Medicine, Mubarak Al-Kabeer Hospital, Jabriya, Kuwait.
Jiazhu PanDepartment of Mathematics and Statistics, University of Strathclyde, Glasgow, UK.
Kobalava D ZhannaDepartment of Internal Medicine with the Subspecialty of Cardiology and Functional Diagnostics Named after V.S. Moiseev, Institute of Medicine, Peoples' Friendship University of Russia (RUDN University), Moscow, Russian Federation.
Maryam RamadhanDepartment of Obstetrics and Gynaecology, Maternity Hospital, Shuwaikh Medical Area, Kuwait.
Mohammad Al SalehDepartment of Medicine, Farwaniya Hospital, Farwaniya, Kuwait.
Mohammed AbdullahDepartment of Infectious Diseases, Infectious Diseases Hospital, Shuwaikh Medical Area, Kuwait.
Naser AlotaibiDepartment of Medicine, Al Adan Hospital, Hadiya, Kuwait.
Noor AlNasrallahDepartment of Medicine, Al Adan Hospital, Hadiya, Kuwait.
Rajesh RajanDepartment of Cardiology, Sabah Al Ahmed Cardiac Centre, Al Amiri Hospital, Kuwait City, Kuwait.ORCID 0000-0002-0249-0440
Soumoud HusseinDepartment of Medicine, Al Amiri Hospital, Kuwait City, Kuwait.
Wael AboelhassanDivision of Gastroenterology, Department of Medicine, Jaber Al Ahmed Hospital, South Surra, Kuwait.
Farwaniya Hospital · KWAdan Hospital · KWAmiri Hospital · KWChest Diseases Hospital · KWUniversity of Strathclyde · GBJahra Hospital · KWKuwait Institute for Medical Specialization · KWMubarak Al Kabeer Hospital · KWPeoples' Friendship University of Russia · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to investigate in-hospital mortality rates in patients with coronavirus disease (COVID-19) according to enoxaparin and heparin use.

methodsThis retrospective cohort study included 962 patients admitted to two hospitals in Kuwait with a confirmed diagnosis of COVID-19. Cumulative all-cause mortality rate was the primary outcome.

resultsA total of 302 patients (males, 196 [64.9%]; mean age, 57.2 ± 14.6 years; mean body mass index, 29.8 ± 6.5 kg/m

conclusionAge, hypertension, pneumonia, therapeutic anticoagulation, and methylprednisolone use were found to be strong predictors of in-hospital mortality. In elderly hypertensive COVID-19 patients on therapeutic anticoagulation were found to have 2.3 times higher risk of in-hospital mortality. All cause in-hospital mortality rate in the therapeutic anticoagulation group was up to 21%.

Indexed as

COVID-19 Drug TreatmentSARS-CoV-2AdultAgedAnticoagulantsEnoxaparinHeparinHospital MortalityHumansMaleMethylprednisoloneMiddle AgedRetrospective StudiesAnticoagulantsEnoxaparinHeparinMethylprednisoloneanticoagulationCOVID-19in-hospital mortalitypneumoniaSARS-CoV-2

Identifiers

PMID36285386
PMCPMC9608030
OpenAlexW4307583704

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.