ArticleRenal failure2022
The relationship between platelet distribution width and new-onset cardiovascular disease events in patients with peritoneal dialysis.
Article in Renal failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Platelet indices and incident CKD in high-risk individuals.Clinical and experimental nephrology · 2026Article
- Association of inflammatory markers with functional outcome after endovascular thrombectomy in anterior circulation stroke: a retrospective study.Frontiers in neurology · 2026Article
- Fibrinogen/albumin ratio is associated with first-ever cardiovascular events in patients with peritoneal dialysis.Annals of medicine · 2025Article
- The relationship of platelet distribution width with all-cause and cardiovascular mortality in peritoneal dialysis patients.Renal failure · 2024Article
- Association between perioperative platelet distribution width changes and postoperative acute kidney injury in patients with renal insufficiency: a retrospective study.BMC nephrology · 2024Article
- The impact of depression on platelet activation, cardiocerebral vascular events and arteriovenous fistula dysfunction in patients undergoing haemodialysis.Scientific reports · 2024Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe global mortality rate from chronic kidney disease (CKD) has increased over the past two decades. Typically, peritoneal dialysis (PD) remains a useful alternative treatment for end-stage renal disease. Cardiovascular disease (CVD) is the main complication in PD patients. In terms of prognosis, it is reported that platelet distribution width (PDW) can predict adverse CVD events. However, the relationship between PDW and new-onset CVD in PD patients is not clear. This study aimed to explore the relationship between PDW and new-onset CVD in PD patients.
methodsThis was a retrospective cohort study, from 4 July 2005 to 31 December 2019, and a total of 1557 patients were recruited. PDW was respectively categorized into two groups: PDW ≤13.2 fL and PDW >13.2 fL. The primary outcome was a new-onset CVD event. Cox proportional hazards models were performed to assess the hazard ratio (HR). Receiver-operating characteristic (ROC) curves were applied to evaluate the predictive accuracy of the PDW on CVD events.
resultsDuring follow-up, 114 new-onset CVD events were recorded. Cox proportional hazards models showed a higher risk of CVD events in patients with high PDW (HR = 1.862 95%CI 1.205-2.877,
conclusionsHigh PDW is associated with new-onset cardiovascular disease events in PD patients.
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