Evidence map›Paper›PMID 36285185›Full record

ArticleSynthetic biology (Oxford, England)2022

Highly-automated, high-throughput replication of yeast-based logic circuit design assessments.

Robert P Goldman, Robert Moseley, Nicholas Roehner, Breschine Cummins, Justin D Vrana, Katie J Clowers, Daniel Bryce, Jacob Beal, Matthew DeHaven, Joshua Nowak and 26 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Synthetic biology (Oxford, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Special issue: reproducibility in synthetic biology.Synthetic biology (Oxford, England) · 2023
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors.

Robert P GoldmanSIFT, LLC, 319 First Ave, North, Suite 400, Minneapolis, MN 55401, USA.ORCID https://orcid.org/0000-0002-5851-4851
Robert MoseleyDepartment of Biology, Box 90338, Duke University, Durham, NC 27708, USA.
Nicholas RoehnerBBN/Raytheon, 10 Moulton Street, Cambridge, MA 02138, USA.
Breschine CumminsDepartment of Mathematical Sciences, Montana State University, P.O. Box 172400, Bozeman, MT 59717-2400, USA.ORCID https://orcid.org/0000-0002-3097-5277
Justin D VranaJust - Evotec Biologics, 401 Terry Ave N, Seattle, WA 98109, USA.ORCID https://orcid.org/0000-0002-0862-0824
Katie J ClowersGinkgo Bioworks, 27 Drydock Ave 8th Floor, Boston, MA 02210, USA.
Daniel BryceSIFT, LLC, 319 First Ave, North, Suite 400, Minneapolis, MN 55401, USA.
Jacob BealBBN/Raytheon, 10 Moulton Street, Cambridge, MA 02138, USA.ORCID https://orcid.org/0000-0002-1663-5102
Matthew DeHavenSIFT, LLC, 319 First Ave, North, Suite 400, Minneapolis, MN 55401, USA.
Joshua NowakStrateos.
Trissha HigaStrateos.
Vanessa BiggersStrateos.
Peter LeeGinkgo Bioworks, 27 Drydock Ave 8th Floor, Boston, MA 02210, USA.
Jeremy P HuntStrateos.
Lorraine MosquedaStrateos.
Steven B HaaseDepartment of Biology, Box 90338, Duke University, Durham, NC 27708, USA.ORCID https://orcid.org/0000-0001-8127-8992
Mark WestonTexas Advanced Computer Center (TACC), University of Texas, 10100 Burnet Rd, Austin, TX 78758, USA.
George ZhengTexas Advanced Computer Center (TACC), University of Texas, 10100 Burnet Rd, Austin, TX 78758, USA.
Anastasia DeckardGeometric Data Analytics, Inc., 343 W Main St, Durham, NC 27701, USA.
Shweta GopaulakrishnanTexas Advanced Computing Center, University of Texas at Austin.
Joseph F StubbsTexas Advanced Computing Center, University of Texas at Austin.
Niall I GaffneyTexas Advanced Computing Center, University of Texas at Austin.
Matthew W VaughnTexas Advanced Computing Center, University of Texas at Austin.
Narendra MaheshriGinkgo Bioworks, 27 Drydock Ave 8th Floor, Boston, MA 02210, USA.
Ekaterina MikhalevGinkgo Bioworks, 27 Drydock Ave 8th Floor, Boston, MA 02210, USA.
Bryan BartleyBBN/Raytheon, 10 Moulton Street, Cambridge, MA 02138, USA.ORCID https://orcid.org/0000-0002-1597-4022
Richard MarkeloffBBN/Raytheon, 10 Moulton Street, Cambridge, MA 02138, USA.
Tom MitchellBBN/Raytheon, 10 Moulton Street, Cambridge, MA 02138, USA.
Tramy NguyenBBN/Raytheon, 10 Moulton Street, Cambridge, MA 02138, USA.
Daniel SumorokBBN/Raytheon, 10 Moulton Street, Cambridge, MA 02138, USA.
Nicholas WalczakBBN/Raytheon, 10 Moulton Street, Cambridge, MA 02138, USA.
Chris MyersDepartment of Electrical, Computer & Energy Engineering, College of Engineering and Applied Science, University of Colorado, Boulder, 425 UCB #1B55, Boulder, CO 80309, USA.
Zach ZundelDepartment of Electrical and Computer Engineering, University of Utah, 50 Central Campus Dr #2110, Salt Lake City, UT 84112, USA.
Benjamin HatchDepartment of Electrical and Computer Engineering, University of Utah, 50 Central Campus Dr #2110, Salt Lake City, UT 84112, USA.
James ScholzDepartment of Electrical and Computer Engineering, University of Utah, 50 Central Campus Dr #2110, Salt Lake City, UT 84112, USA.
John Colonna-RomanoAptima.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe an experimental campaign that replicated the performance assessment of logic gates engineered into cells of

Indexed as

combinatory logicCRISPRhigh-throughput experimentationreplicationyeast

Identifiers

PMID36285185
PMCPMC9583850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.