Evidence map›Paper›PMID 36285149›Full record

ArticleDevelopment & reproduction2022

Styrene Cytotoxicity in Testicular Leydig Cells

Jin-Yong Chung, Ji-Eun Park, Yoon-Jae Kim, Seung-Jin Lee, Wook-Joon Yu, Jong-Min Kim

Open access · diamondAbstract read
In one paragraph

Article in Development & reproduction, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jin-Yong ChungDepartment of Anatomy and Cell Biology, College of Medicine, Dong-A University, Busan 49201, Korea.ORCID https://orcid.org/0000-0001-8149-584X
Ji-Eun ParkDepartment of Anatomy and Cell Biology, College of Medicine, Dong-A University, Busan 49201, Korea.ORCID https://orcid.org/0000-0001-5110-0501
Yoon-Jae KimDepartment of Anatomy and Cell Biology, College of Medicine, Dong-A University, Busan 49201, Korea.ORCID https://orcid.org/0000-0001-5378-9947
Seung-Jin LeeDevelopmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon 34114, Korea.ORCID https://orcid.org/0000-0001-7109-6423
Wook-Joon YuDevelopmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon 34114, Korea.ORCID https://orcid.org/0000-0003-3844-0274
Jong-Min KimDepartment of Anatomy and Cell Biology, College of Medicine, Dong-A University, Busan 49201, Korea.ORCID https://orcid.org/0000-0002-6201-1739
Dong-A University · KRKorea Institute of Toxicology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Styrene is the precursor of polystyrene. Human exposure to styrene could occur in occupational and residential settings and via food intake. Styrene is metabolized to styrene-7,8-oxide by cytochrome P450 enzyme. In the present study, we investigated the cytotoxicity mediated by styrene and styrene-7,8-oxide in TM3 testicular Leydig cells

Indexed as

ApoptosisCaspase-3CytotoxicityLeydig cellsStyreneStyrene-7,8-oxide

Identifiers

PMID36285149
PMCPMC9578320
OpenAlexW4306399761

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.