ArticleCyborg and bionic systems (Washington, D.C.)2021
Self-Assembly of DNA Molecules: Towards DNA Nanorobots for Biomedical Applications.
Article in Cyborg and bionic systems (Washington, D.C.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- 4D nanoimaging-guided smart therapeutics: spatiotemporal control of disease microenvironments.RSC advances · 2026Review
- Next-generation biomedical nanorobots: active design, intelligent control, and translational opportunities in regenerative and minimally invasive medicine.Journal of nanobiotechnology · 2026Review
- Science Outreach: Providing an Authentic Independent Research Opportunity in Materials Science to School Students.Journal of chemical education · 2026Article
- Scalable and sustainable manufacturing of functional DNA nanoassemblies via self-folding circular single-stranded DNA.Nature communications · 2026Article
- Urease-driven nanomotors loaded with sorafenib for magnetically-guided accumulation and deep tissue penetration towards hepatocellular carcinoma therapy via ferroptosis induction.Mikrochimica acta · 2026Article
- Advanced Imaging Strategies Based on Intelligent Micro/Nanomotors.Cyborg and bionic systems (Washington, D.C.) · 2025Review
- A Nanorobotics-Based Approach of Breast Cancer in the Nanotechnology Era.International journal of molecular sciences · 2024Review
- Ultrafast Miniature Robotic Swimmers with Upstream Motility.Cyborg and bionic systems (Washington, D.C.) · 2023Article
- 2D Magnetic Manipulation of a Micro-Robot in Glycerin Using Six Pairs of Magnetic Coils.Micromachines · 2022Article
- Gravity-resisting colloidal collectives.Science advances · 2022Article
- Vision-Based Automated Control of Magnetic Microrobots.Micromachines · 2022Article
- Biohybrid Micro- and Nanorobots for Intelligent Drug Delivery.Cyborg and bionic systems (Washington, D.C.) · 2022Review
- Parallel Manipulation and Flexible Assembly of Micro-SpiralFrontiers in bioengineering and biotechnology · 2022Article
- Multimodal Locomotion and Cargo Transportation of Magnetically Actuated Quadruped Soft Microrobots.Cyborg and bionic systems (Washington, D.C.) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA nanotechnology takes DNA molecule out of its biological context to build nanostructures that have entered the realm of robots and thus added a dimension to cyborg and bionic systems. Spurred by spring-like properties of DNA molecule, the assembled nanorobots can be tuned to enable restricted, mechanical motion by deliberate design. DNA nanorobots can be programmed with a combination of several unique features, such as tissue penetration, site-targeting, stimuli responsiveness, and cargo-loading, which makes them ideal candidates as biomedical robots for precision medicine. Even though DNA nanorobots are capable of detecting target molecule and determining cell fate via a variety of DNA-based interactions both in vitro and in vivo, major obstacles remain on the path to real-world applications of DNA nanorobots. Control over nanorobot's stability, cargo loading and release, analyte binding, and dynamic switching both independently and simultaneously represents the most eminent challenge that biomedical DNA nanorobots currently face. Meanwhile, scaling up DNA nanorobots with low-cost under CMC and GMP standards represents other pertinent challenges regarding the clinical translation. Nevertheless, DNA nanorobots will undoubtedly be a powerful toolbox to improve human health once those remained challenges are addressed by using a scalable and cost-efficient method.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.