Evidence map›Paper›PMID 36284642›Full record

ArticleEuropean heart journal open2022

Left ventricular assessment with artificial intelligence increases the diagnostic accuracy of stress echocardiography.

Jamie M O'Driscoll, William Hawkes, Arian Beqiri, Angela Mumith, Andrew Parker, Ross Upton, Annabelle McCourt, William Woodward, Cameron Dockerill, Nikant Sabharwal and 13 more

Abstract read
In one paragraph

Article in European heart journal open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Artificial Intelligence in Coronary Artery Interventions: Preprocedural Planning and Procedural Assistance.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Jamie M O'DriscollUltromics Ltd, 4630 Kingsgate, Cascade Way, Oxford Business Park South, Oxford OX4 2SU, UK.
William HawkesUltromics Ltd, 4630 Kingsgate, Cascade Way, Oxford Business Park South, Oxford OX4 2SU, UK.
Arian BeqiriUltromics Ltd, 4630 Kingsgate, Cascade Way, Oxford Business Park South, Oxford OX4 2SU, UK.
Angela MumithUltromics Ltd, 4630 Kingsgate, Cascade Way, Oxford Business Park South, Oxford OX4 2SU, UK.
Andrew ParkerUltromics Ltd, 4630 Kingsgate, Cascade Way, Oxford Business Park South, Oxford OX4 2SU, UK.
Ross UptonUltromics Ltd, 4630 Kingsgate, Cascade Way, Oxford Business Park South, Oxford OX4 2SU, UK.
Annabelle McCourtCardiovascular Clinical Research Facility, Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.
William WoodwardCardiovascular Clinical Research Facility, Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.ORCID https://orcid.org/0000-0001-9875-4983
Cameron DockerillCardiovascular Clinical Research Facility, Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.
Nikant SabharwalOxford Heart Centre, Oxford University Hospitals NHS Foundation Trust, Oxford OX3 9DU, UK.ORCID https://orcid.org/0000-0002-1989-947X
Attila KardosDepartment of Cardiology, Milton Keynes University Hospital NHS Foundation Trust, Milton Keynes MK6 5LD, UK.
Daniel X AugustineDepartment of Cardiology, Royal United Hospitals NHS Foundation Trust, Bath BA1 3NG, UK.
Katrin BalkhausenDepartment of Cardiology, Royal Berkshire NHS Foundation Trust, Reading RG1 5AN, UK.
Badrinathan ChandrasekaranDepartment of Cardiology, Great Western Hospitals NHS Foundation Trust, Swindon SN3 6BB, UK.ORCID https://orcid.org/0000-0002-2265-0501
Soroosh FiroozanDepartment of Cardiology, Buckinghamshire Healthcare NHS Trust, High Wycombe HP7 0JD, UK.
Anna MarciniakDepartment of Cardiology, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, Tooting, London SW17 0QT, UK.
Stephen HeitnerKnight Cardiovascular Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Mrinal YadavaKnight Cardiovascular Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Sanjiv KaulKnight Cardiovascular Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Rizwan SarwarUltromics Ltd, 4630 Kingsgate, Cascade Way, Oxford Business Park South, Oxford OX4 2SU, UK.
Rajan SharmaDepartment of Cardiology, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, Tooting, London SW17 0QT, UK.
Gary WoodwardUltromics Ltd, 4630 Kingsgate, Cascade Way, Oxford Business Park South, Oxford OX4 2SU, UK.
Paul LeesonCardiovascular Clinical Research Facility, Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.ORCID https://orcid.org/0000-0001-9181-9297

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: To evaluate whether left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS), automatically calculated by artificial intelligence (AI), increases the diagnostic performance of stress echocardiography (SE) for coronary artery disease (CAD) detection. Methods and results: SEs from 512 participants who underwent a clinically indicated SE (with or without contrast) for the evaluation of CAD from seven hospitals in the UK and US were studied. Visual wall motion scoring (WMS) was performed to identify inducible ischaemia. In addition, SE images at rest and stress underwent AI contouring for automated calculation of AI-LVEF and AI-GLS (apical two and four chamber images only) with Ultromics EchoGo Core 1.0. Receiver operator characteristic curves and multivariable risk models were used to assess accuracy for identification of participants subsequently found to have CAD on angiography. Participants with significant CAD were more likely to have abnormal WMS, AI-LVEF, and AI-GLS values at rest and stress (all Conclusion: AI calculation of LVEF and GLS by contouring of contrast-enhanced and unenhanced SEs at rest and stress is feasible and independently improves the identification of obstructive CAD beyond conventional WMSI.

Indexed as

Artificial intelligenceContrastCoronary artery diseaseEjection fractionGlobal longitudinal strainStress echocardiography

Identifiers

PMID36284642
PMCPMC9580364

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.