Evidence map›Paper›PMID 36284233›Full record

ArticleCell research2023

mTOR gets greasy: lysosomal sensing of cholesterol.

Liron Bar-Peled, Dudley W Lamming

Abstract readComment
In one paragraph

Article in Cell research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Liron Bar-PeledMGH Cancer Center and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. lbar-peled@mgh.harvard.edu.
Dudley W LammingDepartment of Medicine, University of Wisconsin-Madison, Madison, WI, USA. dlamming@medicine.wisc.edu.ORCID 0000-0002-0079-4467

Funding

The regulation of health and longevity by branched-chain amino acidsR01AG056771 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Dudley William Lamming · 2018 to 2026
$3.1M
The regulation of health and longevity by branched-chain amino acidsRF1AG056771 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI LAMMING, DUDLEY WILLIAM · 2023 to 2023
$2.1M
Comparative analysis of geroprotective interventions in established and novel mouse models of Alzheimer's diseaseR01AG062328 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI LAMMING, DUDLEY WILLIAM, MERRINS, MATTHEW J. · 2018 to 2022
$2.0M
Dietary regulation of the hepatic epigenomeR01DK125859 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI DENU, JOHN M, LAMMING, DUDLEY WILLIAM · 2021 to 2023
$1.8M
The regulation of health and longevity by branched-chain amino acidsR56AG056771 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI LAMMING, DUDLEY WILLIAM · 2017 to 2017
$573k
Translation analysis of a novel intervention for diet-induced obesityR21AG061635 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI COLMAN, RICKI J, LAMMING, DUDLEY WILLIAM · 2019 to 2020
$426k
Promoting metabolic health through the reduction of dietary branched chain amino acidsI01BX004031 · VA · WM S. MIDDLETON MEMORIAL VETERANS HOSP · PI LAMMING, DUDLEY WILLIAM · 2018 to 2022
–
BLRD VA I01 BX004031NIA NIH HHS R01 AG056771NIA NIH HHS R01 AG062328NIA NIH HHS R21 AG061635NIA NIH HHS R56 AG056771NIA NIH HHS RF1 AG056771NIDDK NIH HHS R01 DK125859
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CholesterolTOR Serine-Threonine KinasesLysosomesCholesterolTOR Serine-Threonine Kinases

Identifiers

PMID36284233
PMCPMC9977915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.