Evidence map›Paper›PMID 36284141›Full record

ReviewPediatric research2023

Sleep-related breathing disorder in non-infectious pulmonary complications after pediatric allogeneic stem cell transplantation.

Elli-Maija Ukonmaanaho, Turkka Kirjavainen, Laura Martelius, Jouko Lohi, Riitta Karikoski, Minna Koskenvuo, Mervi Taskinen

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pediatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Elli-Maija UkonmaanahoDivision of Pediatric Hematology and Oncology, Oulu University Hospital, Oulu, Finland. elli-maija.ukonmaanaho@ppshp.fi.ORCID http://orcid.org/0000-0001-8436-3922
Turkka KirjavainenDivision of Pediatric Pulmonology, New Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Laura MarteliusDivision of Radiology, New Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Jouko LohiDivision of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Riitta KarikoskiDivision of Pathology, Helsinki University Hospital, Helsinki, Finland.
Minna KoskenvuoDivision of Hematology-Oncology and Stem Cell Transplantation, New Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Mervi TaskinenDivision of Hematology-Oncology and Stem Cell Transplantation, New Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
University of Helsinki · FIHelsinki University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic lung problems are a rare but serious complication of allogeneic hematopoietic stem cell transplantation (HSCT). We studied clinical phenotypes and polysomnography appearance of breathing abnormality in late onset non-infectious pulmonary complications (NIPS).

methodsWe reviewed Finnish national reference database between the years 1999 and 2016. We identified 12 children with most severely decreased pulmonary function and performed polysomnography and 24 aged-matched controls out of 325 performed pediatric allogeneic HSCTs.

resultsAll patients with NIPS had severely decreased pulmonary function already at 6 months post HSCT with median FEV

conclusionsChildren going through allogeneic HSCT who develop severe chronic obstructive lung function are more likely to present with sleep-related hypoxia and hypoventilation than children with restrictive lung function. IMPACT: Children with severe obstructive lung function and chronic lung graft-versus-host disease following hematopoietic stem cell transplantation are more likely to present with sleep-related mild hypoxia and hypoventilation than children with restrictive lung disease. To our knowledge there are no reports on sleep-related breathing disorders and ventilatory function measured by polysomnography in children with pulmonary complications after allogeneic HSCT. Polysomnography may add to the differential diagnostics between patients with BOS and other non-infectious pulmonary complications.

Indexed as

Hematopoietic Stem Cell TransplantationRespiration DisordersSleep Wake DisordersHumansHypoventilationHypoxiaSleepStem Cell Transplantation

Identifiers

PMID36284141
PMCPMC10313514
OpenAlexW4307338084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.