ArticleNature communications2022
Cone opponent functional domains in primary visual cortex combine signals for color appearance mechanisms.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Synaptic Organization of the Primate Retina: Toward a Human Foveal Connectome.Annual review of vision science · 2026Review
- Electrical Microstimulation in Macaque Early Visual Cortex Reveals Causal Links to Color Perception.Neuroscience bulletin · 2026Article
- Approaching a connectome of the human foveal retina.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Gray Anchoring: A New Computational Theory for Biological Color Constancy.Neuroscience bulletin · 2026Article
- Optogenetic stimulation of pyramidal neurons in the rat primary visual cortex modulates ON- and OFF- receptive field areas independently.Scientific reports · 2025Article
- Autistic traits influence aesthetic judgments of abstract color works.BMC psychology · 2025Article
- Color contrast adaptation and compensation in color deficiencies.Journal of vision · 2025Article
- Article
- Interocular suppression in chromoluminance patterns measured with SSVEP.Journal of vision · 2025Article
- High-Resolution Laminar Identification in Macaque Primary Visual Cortex Using Neuropixels Probes.bioRxiv : the preprint server for biology · 2024Article
- A circuit motif for color in the human foveal retina.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Hue and orientation pinwheels in macaque area V4.Journal of neurophysiology · 2024Article
- Binocular receptive-field construction in the primary visual cortex.Current biology : CB · 2024Article
- Unique yellow shifts for small and brief stimuli in the central retina.Journal of vision · 2024Article
- Cone-Opponent Ganglion Cells in the Primate Fovea Tuned to Noncardinal Color Directions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- The neural origin for asymmetric coding of surface color in the primate visual cortex.Nature communications · 2024Article
- Color appearance and the end of Hering's Opponent-Colors Theory.Trends in cognitive sciences · 2023Review
- Dynamic Recruitment of the Feedforward and Recurrent Mechanism for Black-White Asymmetry in the Primary Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Comparative connectomics reveals noncanonical wiring for color vision in human foveal retina.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- It's not easy seeing green: The veridical perception of small spots.Journal of vision · 2023Article
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Authors and funding
5 authors.
Funding
Abstract
Studies of color perception have led to mechanistic models of how cone-opponent signals from retinal ganglion cells are integrated to generate color appearance. But it is unknown how this hypothesized integration occurs in the brain. Here we show that cone-opponent signals transmitted from retina to primary visual cortex (V1) are integrated through highly organized circuits within V1 to implement the color opponent interactions required for color appearance. Combining intrinsic signal optical imaging (ISI) and 2-photon calcium imaging (2PCI) at single cell resolution, we demonstrate cone-opponent functional domains (COFDs) that combine L/M cone-opponent and S/L + M cone-opponent signals following the rules predicted from psychophysical studies of color perception. These give rise to an orderly organization of hue preferences of the neurons within the COFDs and the generation of hue "pinwheels". Thus, spatially organized neural circuits mediate an orderly transition from cone-opponency to color appearance that begins in V1.
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