Observational studyJournal of ultrasound2023
Additional value of Doppler ultrasound to B-mode ultrasound in assessing for uterine intracavitary pathologies among perimenopausal and postmenopausal bleeding women: a multicentre prospective observational study in Vietnam.
Observational study in Journal of ultrasound, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Diagnosis, treatment and clinical outcomes of extrauterine sites of leiomyomatosis: a systematic review.Annals of medicine · 2025Pooled it
- Article
- Management and outcomes of fertility preservation in rare Cowden syndrome-associated endometrial carcinoma: a case series.BMC women's health · 2026Article
- Contrast-enhanced ultrasonography: a potential way for diagnosing cesarean scar pregnancy.Quantitative imaging in medicine and surgery · 2026Article
- Correlation of Histopathological Parameters With Molecular Markers in Carcinoma Endometrium.Cureus · 2026Article
- Factors associated with hysterectomy after failure of levonorgestrel-releasing intrauterine system treatment in women with abnormal uterine bleeding.BMC women's health · 2026Article
- PAX1/JAM3 methylation in cervical exfoliated cells: a robust diagnostic biomarker for cervical high-grade lesions associated with vaginal dysbiosis.BMC women's health · 2026Article
- Artificial Intelligence in the Diagnosis and Imaging-Based Assessment of Pelvic Organ Prolapse: A Scoping Review.Medicina (Kaunas, Lithuania) · 2025Article
- Article
- The Role of Psychological Flexibility and Psychological Factors in Chronic Pelvic Pain Among Women: A Correlational Study.Healthcare (Basel, Switzerland) · 2025Article
- Feasibility and Clinical Outcomes of Robot-Assisted Sacrocolpopexy Using Autologous Round Ligament Grafts: A Novel Non-Mesh Surgical Approach for Pelvic Organ Prolapse.Medicina (Kaunas, Lithuania) · 2025Article
- Changes in Quality of Life, Depression, and Menopausal Symptoms After Surgical Menopause and the Efficacy of Hormone Replacement Therapy in Gynecological Cancer Survivors: A One-Year Prospective Longitudinal Study.Medicina (Kaunas, Lithuania) · 2025Article
- Structural and Hormonal Changes in Reproductive-Age Women Post-COVID-19: A Cross-Sectional Ultrasound and Biochemical Study.Diagnostics (Basel, Switzerland) · 2025Article
- A Decade of Experience in Diagnostic and Conservative Treatment of Endometrial Malignancy-Oncologic and Obstetrical Outcomes from a Referral Oncofertility Center.Diagnostics (Basel, Switzerland) · 2025Article
- Uterine arteriovenous malformation or uterine artery pseudoaneurysm secondary to uterine aspiration in cesarean scar ectopic pregnancy: a case report and review of the literature.Journal of medical case reports · 2025Review
- The Role of Ultrasound in Diagnosing Endometrial Pathologies: Adherence to IETA Group Consensus and Preoperative Assessment of Myometrial Invasion in Endometrial Cancer.Diagnostics (Basel, Switzerland) · 2025Article
- Synchronous Endometrial and Ovarian Adenocarcinomas in a 43-Year-Old Patient Following Infertility Treatment: A Case Report.Diagnostics (Basel, Switzerland) · 2025Article
- Prognostic and Predictive Value of Systemic Inflammatory Markers in Epithelial Ovarian Cancer.Medicina (Kaunas, Lithuania) · 2025Article
- Revolutionizing Surgical Precision: A Case Report on the Articulating Endoscopic Linear Cutter for Laparoscopic Total Hysterectomy.International journal of women's health · 2025Article
- Impact of menopausal status on cognitive function in female papillary thyroid carcinoma patients: a longitudinal propensity score matched study.BMC women's health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine the role of Doppler ultrasonography when combined with B-mode ultrasonography in diagnosing uterine intracavitary pathologies (UIPs) in perimenopausal and postmenopausal bleeding women.
methodsThis multicentre prospective observational study included 150 women aged > 40 years with abnormal uterine bleeding (AUB), who were hospitalised at Hospital X and Hospital Y between June 2016 and June 2019. All participants underwent transvaginal B-mode ultrasound and transvaginal Doppler ultrasound, and the results of sonography were compared to histopathological endpoint.
resultsThe morphological features, structure, margin, border line of the endometrial-mass lesion, intracavitary uterine fluid, and Doppler signal clearly differed between benign and malignant intracavitary pathologies (p < 0.0001). However, echogenicity had a limited value in differentiating among UIPs (p = 0.1). The sensitivity and specificity of the pedicle sign in diagnosing endometrial polyps were 50.0% and 97.6%; for the circular pattern in endometrial fibroids were 46.2% and 100.0%; for the multiple vessel pattern in endometrial cancer were 64.0% and 96.0%; and for the scattered vessel pattern in endometrial hyperplasia were 43.96% and 56.43%, respectively. The additional value of Doppler ultrasound was greater than that of separate B-mode ultrasound in assessing UIPs in our study.
conclusionsB-mode ultrasound used in combination with Doppler as a noninvasive tool was significantly valuable in the diagnostic procedures for UIPs in perimenopausal and postmenopausal bleeding women. Doppler ultrasound and B-mode transvaginal ultrasound should be used together routinely for discrimination between malignant diseases and benign endometrial changes. Further studies are needed to better understand the benefits of combining Doppler ultrasound and B-mode ultrasound in routine sonographic practice.
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