Evidence map›Paper›PMID 36283992›Full record

ArticleArchives of dermatological research2023

Basal cell carcinomas in organ transplant recipients versus the general population: clinicopathologic study.

Nirmala Pandeya, Nancy Huang, Zainab Jiyad, Elsemieke I Plasmeijer, Mandy Way, Nicole Isbel, Scott Campbell, Daniel C Chambers, Peter Hopkins, H Peter Soyer and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of dermatological research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Skin Cancer in Solid Organ Transplant Recipients: A Review.American journal of clinical dermatology · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 3 countries.

Nirmala PandeyaPopulation Health Department, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Nancy HuangPopulation Health Department, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Zainab JiyadPopulation Health Department, QIMR Berghofer Medical Research Institute, Brisbane, Australia.ORCID http://orcid.org/0000-0001-9677-8885
Elsemieke I PlasmeijerPopulation Health Department, QIMR Berghofer Medical Research Institute, Brisbane, Australia.ORCID http://orcid.org/0000-0002-8846-1930
Mandy WayPopulation Health Department, QIMR Berghofer Medical Research Institute, Brisbane, Australia.ORCID http://orcid.org/0000-0003-3444-1907
Nicole IsbelDepartment of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia.ORCID http://orcid.org/0000-0002-9566-7179
Scott CampbellDepartment of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia.ORCID http://orcid.org/0000-0003-1338-2151
Daniel C ChambersQueensland Lung Transplant Service, The Prince Charles Hospital, Brisbane, Australia.ORCID http://orcid.org/0000-0002-9553-5870
Peter HopkinsQueensland Lung Transplant Service, The Prince Charles Hospital, Brisbane, Australia.ORCID http://orcid.org/0000-0003-3261-9345
H Peter SoyerDermatology Research Centre, The University of Queensland Diamantina Institute, The University of Queensland, Brisbane, QLD, Australia.ORCID http://orcid.org/0000-0002-4770-561X
David C WhitemanPopulation Health Department, QIMR Berghofer Medical Research Institute, Brisbane, Australia.ORCID http://orcid.org/0000-0003-2563-9559
Catherine M OlsenPopulation Health Department, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Adele C GreenPopulation Health Department, QIMR Berghofer Medical Research Institute, Brisbane, Australia. adele.green@qimrberghofer.edu.au.ORCID http://orcid.org/0000-0002-2753-4841
QIMR Berghofer Medical Research Institute · AUThe University of Queensland · AU

Funding

National Health and Medical Research Council 552429
6 · The paper itself

Abstract

Organ transplant recipients (OTRs) are at greater risk of basal cell carcinomas (BCCs) than non-OTRs, but histopathologic differences between BCCs in OTRs and the general population are largely unknown. We compared clinicopathologic features of BCCs in OTRs vs the general population in Queensland, Australia. Details of BCC tumors (site, size, level of invasion, subtype, biopsy procedure) were collected from histopathology reports in two prospective skin cancer studies, one in OTRs and one general-population-based. We used log-binomial regression models to estimate age- and sex-adjusted prevalence ratios (PR) with 95% confidence intervals (CIs) for BCC features. Overall, there were 702 BCCs in 200 OTRs and 1725 BCCs in 804 population cases. Of these, 327 tumors in 128 OTRs were higher risk BCCs (any head and neck BCC; ≥ 2 cm on trunk/extremities), more per person than 703 higher risk BCCs in 457 cases in the general population (chi-square p = 0.008). Among head/neck BCCs, OTRs were more likely than general population cases to have BCCs on scalp/ear than on face/lip/neck (PR = 1.5, 95%CI 1.2-1.8). Although aggressive subtypes were less common among higher risk BCCs in OTRs, BCCs invading beyond the dermis were almost twice as prevalent in OTRs (PR = 1.8, 95% CI 1.3-2.6) than the general population.

Indexed as

Basal Cell CarcinomaOrgan TransplantationSkin NeoplasmsExtremitiesHumansProspective StudiesBasal cell carcinomaHistopathologyImmunosuppressionOrgan transplant recipientsSkin cancer

Identifiers

PMID36283992
PMCPMC10085887
OpenAlexW4307337137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.