Evidence map›Paper›PMID 36283888›Full record

ArticleArchives de pediatrie : organe officiel de la Societe francaise de pediatrie2022

Two pediatric cases of multisystem inflammatory-like syndrome following COVID-19 vaccination.

C Collignon, C Frachette, D Callot, Y Pinhas, P Bataille, B Bader-Meunier, L Chouchana, M-L Frémond, Z Belhadjer, M Oualha and 4 more

Abstract read
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In one paragraph

Article in Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

C CollignonPediatric Intensive Care Unit, APHP University Hospital Necker-Enfants malades, Paris, France. Electronic address: charlotte.collignon@aphp.fr.
C FrachettePediatric Nephrology, Rheumatology, Dermatology Unit, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, 69677 Bron, France; Faculty of Medicine, University of Lyon, 69100 Villeurbanne, France; National Referee Centre for Rheumatic and Autoimmune and Systemic Diseases in Children (RAISE), 69677 Bron, France; Lyon Immunopathology Federation LIFE, Hospices Civils de Lyon, 69002 Lyon, France.
D CallotRegional Center of Pharmacovigilance, Department of Pharmacology, Cochin Hospital, AP-HP. Centre - Université de Paris, Paris, France.
Y PinhasDepartment of General Pediatrics and Pediatric Infectious Diseases, Necker-Enfants-Malades University Hospital, APHP, Centre-Université de Paris, Paris, France; Université de Paris, Paris, France.
P BatailleUniversité de Paris, Paris, France; Department of Dermatology, Reference Centre for Genodermatoses and Rare Skin Disease (MAGEC), Hopital Universitaire Necker-Enfants Malades, APHP, Paris, France.
B Bader-MeunierUniversité de Paris, Paris, France; Department of Pediatric Immunology and Rheumatology, AP-HP, Necker Hospital, Paris, France.
L ChouchanaRegional Center of Pharmacovigilance, Department of Pharmacology, Cochin Hospital, AP-HP. Centre - Université de Paris, Paris, France.
M-L FrémondUniversité de Paris, Paris, France; Department of Pediatric Immunology and Rheumatology, AP-HP, Necker Hospital, Paris, France.
Z BelhadjerM3C-Necker Enfants Malades, AP-HP, Paris, France.
M OualhaPediatric Intensive Care Unit, APHP University Hospital Necker-Enfants malades, Paris, France; Université de Paris, Paris, France.
F MoulinPediatric Intensive Care Unit, APHP University Hospital Necker-Enfants malades, Paris, France.
E JavouheyFaculty of Medicine, University of Lyon, 69100 Villeurbanne, France; Pediatric Intensive Care Unit, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, 69677 Bron, France.
A BelotNational Referee Centre for Rheumatic and Autoimmune and Systemic Diseases in Children (RAISE), 69677 Bron, France; Lyon Immunopathology Federation LIFE, Hospices Civils de Lyon, 69002 Lyon, France; Pediatric Nephrology, Rheumatology, Dermatology Unit, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, 69677 Bron, France; Faculty of Medicine, University of Lyon, 69100 Villeurbanne, France.
S RenolleauPediatric Intensive Care Unit, APHP University Hospital Necker-Enfants malades, Paris, France; Université de Paris, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multisystem inflammatory syndrome in children (MIS-C) is a novel post-infectious disease occurring in the context of SARS-CoV2 infection. COVID-19 vaccines have been authorized since December 2020, and adverse events including myocarditis have been reported following vaccination. We describe the cases of two pediatric patients presenting with clinical and laboratory features suggestive of MIS-C a few days after receiving their first dose of the Pfizer BNT162b2 vaccine. The outcome was favorable for both patients (after corticosteroid and immunoglobulin administration for one patient). These cases suggest an association between the COVID-19 vaccine and the occurrence of MIS-C.

Indexed as

COVID-19COVID-19 VaccinesBNT162 VaccineChildHumansRNA, ViralSARS-CoV-2SyndromeSystemic Inflammatory Response SyndromeVaccinationBNT162 VaccineCOVID-19 VaccinesRNA, ViralCase reportCOVID-19 vaccineMultisystem inflammatory syndrome in childrenPediatric intensive care unitSide effect

Identifiers

PMID36283888
PMCPMC9510064

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.