Evidence map›Paper›PMID 36283831›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023

Identification of the Acid-Sensitive Site Critical for Chloral Hydrate (CH) Activation of the Proton-Activated Chloride Channel.

Xiang-Ying Xu, Fei-Fei Zhang, Jun Gan, Mao-Yin Zhang, Zhong-Shan Shen, Qing Guo, Yue Teng, Jun-Wei Ji, Jun-Li Cao, Qiong-Yao Tang and 1 more

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The mechanism of CaThe Journal of biological chemistry · 2025
    Article
  5. Article
  6. Article
  7. Knockout ofInternational journal of ophthalmology · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Xiang-Ying XuJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu Province 221004, China.
Fei-Fei ZhangJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu Province 221004, China.
Jun GanJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu Province 221004, China.
Mao-Yin ZhangDepartment of Anesthesiology, the Affiliated Hospital of Xuzhou Medical University.
Zhong-Shan ShenJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu Province 221004, China.
Qing GuoJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu Province 221004, China.
Yue TengJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu Province 221004, China.
Jun-Wei JiJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu Province 221004, China.
Jun-Li CaoJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu Province 221004, China.ORCID 0000-0002-8932-4743
Qiong-Yao TangJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu Province 221004, China qiongyaotang@hotmail.com zhangzhe70@xzhmu.edu.cn.ORCID 0000-0002-1222-7371
Zhe ZhangJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu Province 221004, China qiongyaotang@hotmail.com zhangzhe70@xzhmu.edu.cn.ORCID 0000-0002-8036-698X
Xuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transmembrane protein TMEM206 was recently identified as the molecular basis of the extracellular proton-activated Cl

Indexed as

Chloral HydrateChloride ChannelsAnimalsChloridesHumansMaleMiceMice, Inbred C57BLProtonsChloral HydrateChloride ChannelsChloridesProtonsbiophysical mechanismchloral hydratePACpH sensitivityTEVC

Identifiers

PMID36283831
PMCPMC9888509
OpenAlexW4307342310

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.