Evidence map›Paper›PMID 36283071›Full record

ArticleThe Journal of organic chemistry2022

Organocatalytic Enantioselective α-Nitrogenation of α,α-Disubstituted Aldehydes in the Absence of a Solvent.

Alejandro Torregrosa-Chinillach, Asier Carral-Menoyo, Enrique Gómez-Bengoa, Rafael Chinchilla

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Photoredox/PyridineJournal of the American Chemical Society · 2025
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alejandro Torregrosa-ChinillachDepartment of Organic Chemistry and Institute of Organic Synthesis (ISO), University of Alicante, PO Box 99, Alicante 03080, Spain.ORCID 0000-0002-4416-9559
Asier Carral-MenoyoDepartment of Organic Chemistry I, University of the Basque Country UPV/EHU, Manuel Lardizabal 3, Donostia-San Sebastián 20018, Spain.
Enrique Gómez-BengoaDepartment of Organic Chemistry I, University of the Basque Country UPV/EHU, Manuel Lardizabal 3, Donostia-San Sebastián 20018, Spain.ORCID 0000-0002-8753-3760
Rafael ChinchillaDepartment of Organic Chemistry and Institute of Organic Synthesis (ISO), University of Alicante, PO Box 99, Alicante 03080, Spain.ORCID 0000-0002-9894-1671

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A highly efficient enantioselective α-nitrogenation method of α,α-disubstituted aldehydes with azodicarboxylates promoted by a chiral carbamate-monoprotected cyclohexa-1,2-diamine as organocatalyst has been developed. The process was carried out without any solvent, and the corresponding α,α-disubstituted α-nitrogenated aldehydes were obtained with excellent yields and enantioselectivities up to 99%

Indexed as

AldehydesDiaminesCatalysisSolventsStereoisomerismAldehydesDiaminesSolvents

Identifiers

PMID36283071
PMCPMC9639010

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.