ArticleJournal of periodontal research2023
Periodontitis and edentulism as risk indicators for mortality: Results from a prospective cohort study with 20 years of follow-up.
Article in Journal of periodontal research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Dentures and the oral microbiome: Unraveling the hidden impact on edentulous and partially edentulous patients - a systematic review and meta-analysis.Evidence-based dentistry · 2025Pooled it
- Assessment of Oral Health-Related Quality of Life (OHRQoL) and Factors Influencing Oral Hygiene Habits in Complete Denture Patients.Dentistry journal · 2026Article
- Economic Impact of Periodontitis: Global, Regional and National Estimates of Periodontal Expenditure, With Forecasts to 2050.Journal of periodontal research · 2026Article
- Tregs and persistentFrontiers in oral health · 2026Article
- Using search engine analytics to identify public interest and needs in periodontal disease: a retrospective comparative search term analysis of the keywords "periodontitis" and "gingivitis" for the years 2008-2025 in 5 different countries.Frontiers in digital health · 2026Article
- Multi-Omics Signatures of Periodontitis and Periodontal Therapy on the Oral and Gut Microbiome.Journal of periodontal research · 2025Article
- Impact of lifestyle behaviors on clinical outcomes of steps 1 and 2 of periodontal therapy in stage iii-iv periodontitis: a cohort study.Clinical oral investigations · 2025Article
- Genetic and Epigenetic Biomarkers for the Early Oral Cancerization Risk in Periodontitis Patients.Current issues in molecular biology · 2025Review
- Oral Microbiome Signatures in Periodontitis and Edentulism-A Population-Based Study.Journal of periodontal research · 2025Article
- The Balance and Imbalance of Microbial Communities: Oral-Gut Microbiota and Colorectal Cancer.American journal of clinical oncology · 2025Review
- Periodontal Status and Gingival Crevicular FluidJournal of clinical medicine · 2025Article
- Dental, Oral and General Health of Geriatric In-Hospital Patients Before Immediate Prosthetic Treatment: A Retrospective Cohort Study.Dentistry journal · 2025Article
- Correlation Between Sarcopenia and Oral Health in Patients on Chronic Hemodialysis.Life (Basel, Switzerland) · 2025Article
- Edentulism or Poor Oral Hygiene: Which Is the Stronger Predictor for All-Cause Mortality?Journal of clinical medicine · 2025Article
- Periodontitis and risk of cancer: Mechanistic evidence.Periodontology 2000 · 2024Review
- Modulation of allograft immune responses by Porphyromonas gingivalis lipopolysaccharide administration in a rat model of kidney transplantation.Scientific reports · 2024Article
- From Basic Science to Clinical Practice: A Review of Current Periodontal/Mucogingival Regenerative Biomaterials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Periodontitis and systemic inflammation as independent and interacting risk factors for mortality: evidence from a prospective cohort study.BMC medicine · 2023Article
- The co-occurrence of the two main oral diseases: periodontitis and dental caries.Clinical oral investigations · 2023Article
- Pocket closure after repeated subgingival instrumentation: a stress test to the EFP guideline for stage III-IV periodontitis.Clinical oral investigations · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the association between periodontitis and edentulism with cardiovascular disease (CVD) and all-cause mortality.
methodsBaseline data of 506 subjects including 256 angiographically verified coronary artery disease patients and 250 matched participants in cardiovascular health from the Kuopio Oral Health and Heart study were collected from 1995-1996. Mortality data were accrued until May 31, 2015, and related to baseline periodontal health and edentulism, assessed as exposure and collected by means of clinical and radiographic examination by a single examiner. Cox proportional hazards regression models were fit using covariates such as age, gender, smoking, BMI, and education. The final sample size for the periodontitis models ranged from 358 to 376, while the edentate models included 413 to 503 subjects for CVD and all-cause mortality, respectively with no missing values in the predictor, confounders, and outcome.
resultsThe strongest association was found between edentulism and CVD and all-cause mortality (HR: 1.9
conclusionsEdentulism considered as a poor oral health marker was associated strongly with CVD mortality while periodontitis was not.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.