Evidence map›Paper›PMID 36282746›Full record

SynthesisDevelopmental psychobiology2022

Early childhood stress responses to psychosocial stressors: The state of the science.

Randi A Bates, Lisa Militello, Erin Barker, Hugo Gonzalez Villasanti, Kammi Schmeer

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Developmental psychobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Randi A BatesCollege of Nursing, University of Cincinnati, Cincinnati, Ohio, USA.ORCID 0000-0002-6672-8155
Lisa MilitelloCollege of Nursing, The Ohio State University, Columbus, Ohio, USA.
Erin BarkerCollege of Nursing, University of Cincinnati, Cincinnati, Ohio, USA.ORCID 0000-0001-8361-6481
Hugo Gonzalez VillasantiCrane Center for Early Childhood Research and Policy, The Ohio State University, Columbus, Ohio, USA.
Kammi SchmeerCrane Center for Early Childhood Research and Policy, The Ohio State University, Columbus, Ohio, USA.
The Ohio State University · USUniversity of Cincinnati Medical Center · USOhio Department of Education · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this systematic review was to better understand whether and to what extent psychosocial stressors are associated with hypothalamic-pituitary-adrenal axis or autonomic nervous system stress responses in young children (1-6 years of age). Studies were classified by psychosocial stressors from the ecobiodevelopmental model: social and economic resources, maternal mental health, parent-child relationships, and the physical environment. Of the 2388 identified studies, 32 met full inclusion criteria, including over 9107 children. Child physiologic stress responses were measured as hair and urinary cortisol and cortisone, salivary diurnal and reactive cortisol, salivary reactive alpha-amylase, and respiratory sinus arrhythmia. There were 107 identified relations between psychosocial stressors and physiologic stress responses. Nearly two thirds of these relations suggested that children have dysregulated stress responses as either significantly blunted (n = 27) or increased (n = 37); 43 relations were not significant. Children most consistently had significantly dysregulated stress responses if they experienced postnatal maternal depression or anxiety. Some reasons for the mixed findings may be related to characteristics of the child (i.e., moderators) or stressor, how the stress response or psychosocial stressor was measured, unmeasured variables (e.g., caregiving buffering), researcher degrees of freedom, or publication bias.

Indexed as

CortisonePituitary-Adrenal Systemalpha-AmylasesChild, PreschoolHumansHydrocortisoneHypothalamo-Hypophyseal SystemSalivaStress, Psychologicalalpha-AmylasesCortisoneHydrocortisoneautonomic nervous systemchildparent-child relationspituitary adrenal systemstress

Identifiers

PMID36282746
PMCPMC9543576
OpenAlexW4294647550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.