Evidence map›Paper›PMID 36282481›Full record

ArticleBrain and behavior2022

Clinical features and power spectral entropy of electroencephalography in Wilson's disease with dystonia.

Shaoru Zhang, Aiqun Liu, Zhihua Zhou, Zheng Huang, Jing Cheng, Danping Chen, Qizhi Zhong, Qingyun Yu, Zhongxing Peng, Mingfan Hong

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Shaoru ZhangDepartment of Neurology, The First Affiliated Hospital, Clinical Medicine College of Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.ORCID 0000-0002-9804-994X
Aiqun LiuDepartment of Neurology, The First Affiliated Hospital, Clinical Medicine College of Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
Zhihua ZhouDepartment of Neurology, The First Affiliated Hospital, Clinical Medicine College of Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.ORCID 0000-0001-6262-6365
Zheng HuangDepartment of Neurology, The First Affiliated Hospital, Clinical Medicine College of Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
Jing ChengDepartment of Neurology, The First Affiliated Hospital, Clinical Medicine College of Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
Danping ChenDepartment of Neurology, The First Affiliated Hospital, Clinical Medicine College of Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
Qizhi ZhongDepartment of Neurology, The First Affiliated Hospital, Clinical Medicine College of Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
Qingyun YuDepartment of Neurology, The First Affiliated Hospital, Clinical Medicine College of Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
Zhongxing PengDepartment of Neurology, The First Affiliated Hospital, Clinical Medicine College of Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
Mingfan HongDepartment of Neurology, The First Affiliated Hospital, Clinical Medicine College of Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
Guangdong Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the clinical features and power spectral entropy (PSE) of electroencephalography signals in Wilson's disease (WD) patients with dystonia.

methodsSeveral scale evaluations were performed to assess the clinical features of WD patients. Demographic information and electroencephalography signals were obtained in all subjects.

results34 WD patients with dystonia were recruited in the case group and 24 patients without dystonia were recruited in the control group. 20 healthy individuals were included in the healthy control group. The mean body mass index (BMI) in the case group was significantly lower than that in the controls (p < .05). The case group had significantly higher SAS, SDS, and Bucco-Facial-Apraxia Assessment scores (p < .05). Total BADS scores in the case group were lower than those in the control group (p < .01). Note that 94.11% of the case group presented with dysarthria and 70.59% of them suffered from dysphagia. Dysphagia was mainly related to the oral preparatory stage and oral stage. Mean power spectral entropy (PSE) values in the case group were significantly different (p < .05) from those in the control group and the healthy group across the different tasks.

conclusionsThe patients with dystonia were usually accompanied with low BMI, anxiety, depression, apraxia, executive dysfunction, dysarthria and dysphagia. The cortical activities of the WD patients with dystonia seemed to be more chaotic during the eyes-closed and reading tasks but lower during the swallowing stages than those in the control group.

Indexed as

DystoniaHepatolenticular DegenerationApraxiasCase-Control StudiesDeglutition DisordersDysarthriaElectroencephalographyEntropyHumansdystoniaelectroencephalographyexecutive dysfunctionpower spectral entropy (PSE)Wilson's disease

Identifiers

PMID36282481
PMCPMC9759124
OpenAlexW4307228130

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.