Evidence map›Paper›PMID 36281739›Full record

ArticleClinical and translational medicine2022

ABO gene editing for the conversion of blood type A to universal type O in Rh

Paolo Petazzi, Laia Miquel-Serra, Sergio Huertas, Cecilia González, Neus Boto, Eduardo Muñiz-Diaz, Pablo Menéndez, Ana Sevilla, Núria Nogués

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Paolo PetazziJosep Carreras Leukemia Research Institute, Barcelona, Spain.
Laia Miquel-SerraImmunohematology Laboratory, Barcelona, Spain.
Sergio HuertasImmunohematology Laboratory, Barcelona, Spain.
Cecilia GonzálezImmunohematology Laboratory, Barcelona, Spain.
Neus BotoImmunohematology Laboratory, Barcelona, Spain.
Eduardo Muñiz-DiazImmunohematology Laboratory, Barcelona, Spain.
Pablo MenéndezJosep Carreras Leukemia Research Institute, Barcelona, Spain.
Ana SevillaDepartment of Cell Biology, Physiology and Immunology, Faculty of Biology, University of Barcelona, Barcelona, Spain.ORCID 0000-0002-9251-4759
Núria NoguésImmunohematology Laboratory, Barcelona, Spain.
Vall d'Hebron Institut de Recerca · ESUniversitat Autònoma de Barcelona · ESImmune Regulation (United Kingdom) · GBInstitució Catalana de Recerca i Estudis Avançats · ESInstitut de Biomedicina de la Universitat de BarcelonaJosep Carreras Leukaemia Research Institute · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The limited availability of red cells with extremely rare blood group phenotypes is one of the global challenges in transfusion medicine that has prompted the search for alternative self-renewable pluripotent cell sources for the in vitro generation of red cells with rare blood group types. One such phenotype is the Rh

Indexed as

Blood Group AntigensInduced Pluripotent Stem CellsBlood DonorsFemaleGene EditingHumansRh-Hr Blood-Group SystemBlood Group AntigensRh-Hr Blood-Group SystemABOCRISPRgene editioniPSCrare blood groupsRhnulltransfusion medicine

Identifiers

PMID36281739
PMCPMC9593258
OpenAlexW4307404635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.