Evidence map›Paper›PMID 36281512›Full record

ArticleAnnals of laboratory medicine2023

Comparative Analysis of the Molecular Characteristics of Group B

Yangsoon Lee, Hye Gyung Bae, Dongju Won, Woobin Yun, Hyukmin Lee, Jong Rak Choi, Young Uh, Kyungwon Lee

Open access · diamondAbstract read
In one paragraph

Article in Annals of laboratory medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Epidemiology of NontyphoidalAnnals of laboratory medicine · 2025
    Article
  5. Group BJournal of Korean medical science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yangsoon LeeDepartment of Laboratory Medicine, Hanyang University College of Medicine, Seoul, Korea.ORCID 0000-0003-3821-3741
Hye Gyung BaeSeoul Clinical Laboratories, Yongin, Korea.ORCID 0000-0001-6399-9091
Dongju WonDepartment of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0002-0084-0216
Woobin YunDepartment of Laboratory Medicine, Graduate School of Medical Sciences, Brain, Korea 21 Project, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0001-8785-7207
Hyukmin LeeDepartment of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0002-8523-4126
Jong Rak ChoiDepartment of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0002-0608-2989
Young UhDepartment of Laboratory Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.ORCID 0000-0002-2879-7870
Kyungwon LeeSeoul Clinical Laboratories, Yongin, Korea.ORCID 0000-0003-3788-2134
Yonsei University · KRHanyang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The incidence of early- and late-onset sepsis and meningitis in neonates due to maternal rectovaginal group B Methods: Seventy-five GBS isolates collected from pregnant Korean women visiting Wonju Severance Christian Hospital, Wonju, Korea between 2017 and 2019 were subjected to WGS using the NovaSeq 6000 system (Illumina, San Diego, CA, USA). Multilocus sequence types, serotypes, antimicrobial resistance genes, and hemolysin operon mutations were determined by WGS, and the latter three were compared with the results of conventional phenotypic methods. Results: The predominant lineage was CC1 (37.3%), followed by CC19 (32.0%), CC12 (17.3%), and CC17 (4.0%). All isolates were cps typeable (100%, (75/75), and 89.3% of cps genotypes (67/75) were concordant with serotypes obtained using latex agglutination. The cps genotypes of the 75 isolates were serotypes III (24.0%), V (22.7%), and VIII (17.3%). All isolates harboring intact Conclusions: The low prevalence of CC17 GBS colonization may explain the low frequency of neonatal GBS infections. WGS is a useful tool for simultaneous genotyping and antimicrobial resistance determination.

Indexed as

Pregnant PeopleStreptococcal InfectionsAnti-Bacterial AgentsErythromycinFemaleHemolysin ProteinsHumansInfant, NewbornMultilocus Sequence TypingPregnancyStreptococcus agalactiaeTetracyclineVirulence FactorsAnti-Bacterial AgentsErythromycinHemolysin ProteinsTetracyclineVirulence FactorsGroup B StreptococcusNeonateSepsisSerotypeWhole-genome sequencing

Identifiers

PMID36281512
PMCPMC9618906
OpenAlexW4307342105

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.