Evidence map›Paper›PMID 36281486›Full record

Observational studyJournal of Korean medical science2022

Maternal and Neonatal Outcomes in Pregnant Women With Coronavirus Disease 2019 in Korea.

Youseung Chung, Eun Jin Kim, Hee-Sung Kim, Kyung-Hwa Park, Ji Hyeon Baek, Jungok Kim, Ji Yeon Lee, Chang-Seop Lee, Seungjin Lim, Shin-Woo Kim and 9 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of Korean medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 14 institutions in 1 country.

Youseung ChungDivision of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-6568-0516
Eun Jin KimDivision of Infectious Diseases, Department of Internal Medicine, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0001-7008-0497
Hee-Sung KimDepartment of Internal Medicine, Chungbuk National University College of Medicine, Cheongju, Korea.ORCID https://orcid.org/0000-0001-7559-4438
Kyung-Hwa ParkDepartment of Infectious Diseases, Chonnam National University Medical School, Gwangju, Korea.ORCID https://orcid.org/0000-0003-2836-6963
Ji Hyeon BaekDivision of Infectious Diseases, Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea.ORCID https://orcid.org/0000-0002-1783-6950
Jungok KimDepartment of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0002-0694-1579
Ji Yeon LeeDepartment of Infectious Diseases, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-2788-1392
Chang-Seop LeeDepartment of Internal Medicine, Jeonbuk National University Medical School, Jeonju, Korea.ORCID https://orcid.org/0000-0002-2897-2202
Seungjin LimDivision of Infectious Diseases, Department of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea.ORCID https://orcid.org/0000-0001-7939-9744
Shin-Woo KimDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0002-3755-8249
Eu Suk KimDivision of Infectious Diseases, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.ORCID https://orcid.org/0000-0001-7132-0157
Hye Jin ShiDivision of Infectious Disease, Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Korea.ORCID https://orcid.org/0000-0002-7571-8485
Shin Hee HongDivision of Infectious Disease, Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Korea.ORCID https://orcid.org/0000-0003-2001-7574
Jae-Bum JunDivision of Infectious Diseases, Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.ORCID https://orcid.org/0000-0001-9752-7682
Kyung-Wook HongDepartment of Internal Medicine, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Korea.ORCID https://orcid.org/0000-0002-3227-9558
Jae-Phil ChoiDivision of Infectious Disease, Department of Internal Medicine, Seoul Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0003-4805-7930
Jinyeong KimDivision of Infectious Disease, Department of Internal Medicine, Hanyang University Guri Hospital, Guri, Korea.ORCID https://orcid.org/0000-0002-2360-7038
Kyung Sook YangDepartment of Biostatistics, Korea University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3960-6072
Young Kyung YoonDivision of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. young7912@korea.ac.kr.ORCID https://orcid.org/0000-0001-8435-935X
Korea University · KRChungnam National University · KRGachon University Gil Medical Center · KRSeoul National University Bundang Hospital · KRChonnam National University Hospital · KRChungbuk National University · KRGyeongsang National University Hospital · KRInha University · KRJeonbuk National University · KRKeimyung University · KRKyungpook National University · KRPusan National University Yangsan Hospital · KRSeoul Medical Center · KRUlsan College · KR

Funding

Korea Health Industry Development Institute HI20C0384Korea University Medicine O2001221
6 · The paper itself

Abstract

backgroundThis study aimed to describe the maternal, obstetrical, and neonatal outcomes in pregnant women with coronavirus disease 2019 (COVID-19) and identify the predictors associated with the severity of COVID-19.

methodsThis multicenter observational study included consecutive pregnant women admitted because of COVID-19 confirmed using reverse transcriptase-polymerase chain reaction (RT-PCR) test at 15 hospitals in the Republic of Korea between January 2020 and December 2021.

resultsA total of 257 women with COVID-19 and 62 newborns were included in this study. Most of the patients developed this disease during the third trimester. Nine patients (7.4%) developed pregnancy-related complications. All pregnant women received inpatient treatment, of whom 9 (3.5%) required intensive care, but none of them died. The gestational age at COVID-19 diagnosis (odds ratio [OR], 1.096, 95% confidence interval [CI], 1.04-1.15) and parity (OR, 1.703, 95% CI, 1.13-2.57) were identified as significant risk factors of severe diseases. Among women who delivered, 78.5% underwent cesarean section. Preterm birth (38.5%), premature rupture of membranes (7.7%), and miscarriage (4.6%) occurred, but there was no stillbirth or neonatal death. The RT-PCR test of newborns' amniotic fluid and umbilical cord blood samples was negative for severe acute respiratory syndrome coronavirus 2.

conclusionAt the time of COVID-19 diagnosis, gestational age and parity of pregnant women were the risk factors of disease severity. Vertical transmission of COVID-19 was not observed, and maternal severity did not significantly affect the neonatal prognosis.

Indexed as

COVID-19Pregnancy Complications, InfectiousPremature BirthCesarean SectionCOVID-19 TestingFemaleHumansInfant, NewbornInfectious Disease Transmission, VerticalPregnancyPregnancy OutcomePregnant PeopleRNA-Directed DNA PolymeraseRNA-Directed DNA PolymeraseCoronavirus Disease 2019NeonatePregnancySevere Acute Respiratory Syndrome Coronavirus 2

Identifiers

PMID36281486
PMCPMC9592939
OpenAlexW4297152229

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.