Evidence map›Paper›PMID 36281465›Full record

ArticleBioMed research international2022

Arzugül Tanas, Özlem Özdemir Tozlu, Tuğba Gezmiş, Ahmet Hacimüftüoğlu, A M Abd El-Aty, Onur Ceylan, Adil Mardinoğlu, Hasan Türkez

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Efficient gene delivery admitted by small metabolites specifically targeting astrocytes in the mouse brain.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
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  7. Frontiers in nutrition · 2025
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  8. Article
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  10. Article
  11. Article
  12. Article
  13. A comparative metabolomics analysis of domestic yak (Frontiers in veterinary science · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Arzugül TanasDepartment of Molecular Biology and Genetics, Erzurum Technical University, Erzurum, Turkey.
Özlem Özdemir TozluDepartment of Molecular Biology and Genetics, Erzurum Technical University, Erzurum, Turkey.ORCID https://orcid.org/0000-0002-5472-8174
Tuğba GezmişDepartment of Molecular Biology and Genetics, Erzurum Technical University, Erzurum, Turkey.
Ahmet HacimüftüoğluDepartment of Medical Pharmacology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
A M Abd El-AtyDepartment of Medical Pharmacology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
Onur CeylanDepartment of Medical Pathology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
Adil MardinoğluScience for Life Laboratory, KTH-Royal Institute of Technology, Stockholm SE-17121, Sweden.ORCID https://orcid.org/0000-0002-4254-6090
Hasan TürkezDepartment of Medical Biology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
Atatürk University · TRErzurum Technical University · TRKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by behavioral and psychological symptoms in addition to cognitive impairment and loss of memory. The exact pathogenesis and genetic background of AD are unclear and there remains no effective treatment option. Sarcosine, an n-methyl derivative of glycine, showed a promising therapeutic strategy for some cognitive disorders. To our knowledge, the impacts of sarcosine supplementation against AD have not yet been elucidated. Therefore, we aimed to determine the neuroprotective potential of sarcosine in

Indexed as

Alzheimer DiseaseNeuroprotective AgentsAluminumAluminum ChlorideAmyloid Precursor Protein SecretasesAnimalsAntioxidantsAspartic Acid EndopeptidasesRatsRats, WistarSarcosineTumor Necrosis Factor-alphaAluminumAluminum ChlorideAmyloid Precursor Protein SecretasesAntioxidantsAspartic Acid EndopeptidasesNeuroprotective AgentsSarcosineTumor Necrosis Factor-alpha

Identifiers

PMID36281465
PMCPMC9587910
OpenAlexW4306294633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.